Göttinger Graduiertenschule für Neurowissenschaften, Biophysik und Molekulare Biowissenschaften

Gruber, Oliver, Prof. Dr. med.*

Professor, Department of Psychiatry and Psychotherapy


  • 1995 - 1998 Resident, Department of Psychiatry and Psychotherapy, Friedrich-Wilhelms-University, Bonn
  • 1997 - 1998 Assistant Doctor and Postdoctoral Research Fellow, Department of Neurology, Heinrich-Heine-University, Düsseldorf, and Institute of Medicine at Research Center Jülich
  • 1998 – 2001 Assistant doctor and Postdoctoral Research Fellow, MPI of Cognitive and Brain Sciences, Leipzig / Day-care Clinic for Cognitive Neurology, University of Leipzig
  • 2001 – 2003 Assistant doctor and Postdoctoral Research Fellow, Dept. of Psychiatry III, University of Ulm
  • 2003 - 2004 Group Leader and Head of Neuroimaging Lab, Department of Psychiatry and Psychotherapy, University of Homburg
  • 2004 - 2007 Junior Professor of Cognitive Neuroscience in Psychiatry, Specialist Registrar, Department of Psychiatry and Psychotherapy, University of Homburg
  • 2007 - 2012 Deputy Chairman and Assistant Medical Director, Department of Psychiatry and Psychotherapy, Georg August University Göttingen
  • 2007 - present Professor of Systems Neuroscience and Psychiatry, Head of the Centre for Translational Research in Systems Neuroscience and Clinical Psychiatry, Department of Psychiatry and Psychotherapy, Georg August University Göttingen



Major Research Interests


  • Translational Neuroimaging: Identification of neurofunctional endophenotypes of schizophrenic and affective disorders; Development of neuroimaging biomarkers for differential diagnosis and optimization of treatment strategies Affective, Cognitive, and Social Neuroscience
  • Genomic and Epigenomic Neuroimaging: Neurofunctional endophenotype-based genetic and epigenetic association studies in schizophrenic and affective disorders
  • Systems Neuroscience and Clinical Neuroimaging: Pathomechanisms of schizophrenic and affective disorders in dynamically interacting key neural systems




Homepage Department/Research Group

http://www.psychiatrie.med.uni-goettingen.de/content/forschung/256.html



Selected Publications


  • Diekhof, E.K. & Gruber, O. (2010) When desire collides with reason: functional interactions between anteroventral prefrontal cortex and nucleus accumbens underlie the human ability to resist impulsive desires. Journal of Neuroscience, 30 (4), 1488-1493.
  • Gruber, O., Tost, H., Henseler, I., Schmael, C., Scherk, H., Ende, G., Ruf, M., Falkai, P., & Rietschel, M. (2010) Pathological amygdala activation during working memory performance: evidence for a pathophysiological trait marker in bipolar affective disorder. Human Brain Mapping, 31:115-125.
  • Pajonk, F.G., Wobrock, T., Gruber, O., Scherk, H., Berner, D., Kaizl, I., Kierer, A., Müller, S., Oest, M., Meyer, T., Backens, M., Schneider-Axmann, T., Thornton, A.E., Honer, W.G. & Falkai, P. (2010) Hippocampal plasticity in response to exercise in schizophrenia. Archives of General Psychiatry, 67(2), 133-143.
  • Gruber, O. & von Cramon, D. Y. (2003) The functional neuroanatomy of human working memory revisited ? evidence from 3T-fMRI studies using classical domain-specific interference tasks. NeuroImage, 19:797-809.
  • Gruber, O., Indefrey, P., Steinmetz, H. & Kleinschmidt, A. (2001) Dissociating neural correlates of cognitive components in mental calculation. Cerebral Cortex, 11:350-359.