Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und Molekulare Biowissenschaften

Prof. Dr. Stefan Klumpp


  • 1999 Diploma in Physics, University of Heidelberg, Germany
  • 2003 Dr. rer. nat., Physics, University of Potsdam, Germany
  • 2004 – 2005 Research associate, MPI of Colloids and Interfaces, Potsdam, Germany
  • 2006 – 2009 Postdoc, University of California, San Diego, USA
  • 2009 – 2016 Group leader, MPI of Colloids and Interfaces, Potsdam, Germany
  • since 2015 Professor of Theoretical Biophysics, Georg August University, Göttingen, Germany



Major Research Interests


    Biological processes must obey the laws of physics, but are also subject to functional requirements and shaped by the forces of evolution. Our group is interested in how functional requirements are implemented within the given physical constraints. To that end, we develop theoretical tools to describe complex regulatory systems and their coupling to the cellular context. Topics of specific interest are
    - molecular machines (cytoskeletal motors, RNA polymerases, ribosomes),
    - gene circuits and cell growth,
    - (bacterial) cell motility.




Homepage Department/Research Group
http://www.uni-goettingen.de/de/527801.html


Selected Recent Publications


  • Klumpp S, Lefèvre CT, Bennet M, Faivre D (2019) Swimming with magnets: from biological organisms to synthetic devices, Phys. Rep. 789, 1-54

  • Roy A, Klumpp S (2018) Simulating genetic circuits in bacterial populations with growth heterogeneity, Biophys. J. 114, 484-492

  • Gomez D, Klumpp S (2016) Facilitated diffusion in the presence of obstacles on the DNA, Phys. Chem. Chem. Phys. 18, 11184-11192

  • Bierbaum V, Klumpp S (2015) Impact of the cell division cycle on gene circuits. Phys. Biol. 12, 066003

  • Klumpp S Keller C, Berger F, Lipowsky R (2015) Cooperative phenomena of multiple molecular motors, in: Multiscale Modeling in Biomechanics and Mechanobiology. edited by S. De, W. Hwang, E. Kuhl (Springer, London) pp. 27-61

  • Marathe R, Meel C, Schmidt NC, Dewenter L, Kurre R, Greune L, Schmidt MA, Müller MJI, Lipowsky R, Maier B, Klumpp S (2014) Bacterial twitching motility is coordinated by a two-dimensional tug-of-war with directional memory, Nature Commun. 5, 3759