Göttingen Graduate School for Neurosciences, Biophysics, and Molecular Biosciences

Frahm, Jens, Prof. Dr.

Director, Biomedizinische NMR Forschungs GmbH (not-for-profit) at the Max Planck Institute for Biophysical Chemistry


  • 1974 Diploma in Physics, Univ. of Göttingen
  • 1977 Doctorate in Physical Chemistry, Univ. of Göttingen
  • 1977-1982 Postdoctoral Researcher, MPI for Biophysical Chemistry
  • 1982-1992 Head, Independent Research Group ‘Biomedizinische NMR’ (BMFT grant)
  • since 1993 Director, Biomedizinische NMR Forschungs GmbH (not-for-profit, based on group’s patents)
  • 1994 Habilitation, Faculty of Chemistry, Univ. of Göttingen
  • since 1997 Adjunct Professor, Faculty of Chemistry, Univ. of Göttingen
  • since 2011 External Scientific Member, MPI for Dynamic and Self-Organization



Major Research Interests


  • Development and biomedical applications of magnetic resonance imaging (MRI): noninvasive studies of structure and function at the system level (animals and humans)
  • Methodology: non-Cartesian MRI, parallel MRI, numerical reconstruction techniques, real-time MRI, cardiovascular MRI
  • Human neuroscience: functional neuroimaging, neuro-feedback, fiber tractography
  • Animal studies: models of human brain disorders, nonhuman primates, genetically modified mice



Homepage Department/Research Group

http://www.biomednmr.mpg.de/



Selected Recent Publications


  • Z. Tan, V. Roeloffs, D. Voit, A.A. Joseph, M. Untenberger, K.D. Merboldt, J. Frahm. Model-based reconstruction for real-time phase-contrast flow MRI ? Improved spatiotemporal accuracy. Magn. Reson. Med., doi:10.1002/mrm.26192 (2016).
  • P.W. Iltis, J. Frahm, D. Voit, A.A. Joseph, R. Burke, E. Altenmüller. Inefficiencies in motor strategies of horn players with embouchure dystonia: comparisons to elite performers. Med. Probl. Perform. Art. 31, 69-77 (2016).
  • T. Watanabe, J. Frahm, T. Michaelis. Amide proton signals as pH indicator for in vivo MRS and MRI of the brain ? Responses to hypercapnia and hypothermia. NeuroImage, doi: 10.1016/j.neuroimage.2016.03.013 (2016).
  • M. Untenberger, Z. Tan, D. Voit, A.A. Joseph, V. Roeloffs, K.D. Merboldt, S. Schaetz, J. Frahm. Advances in real-time phase-contrast flow MRI using asymmetric radial gradient echoes. Magn. Reson. Med. 75, 1901-1908 (2016).
  • S. Hofer, X. Wang, V. Roeloffs, J. Frahm. Single-shot T1 mapping of the corpus callosum: A rapid characterization of fiber bundle anatomy. Front. Neuroanat. 9:57 (2015).
  • S. Dreha-Kulaczewski, A.A. Joseph, K.D. Merboldt, H.-C. Ludwig, J. Gärtner, J. Frahm. Inspiration is the major regulator of human CSF flow. J. Neurosci. 35, 2485-2491 (2015).