Göttingen Graduate School for Neurosciences, Biophysics, and Molecular Biosciences
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Stühmer, Walter, Prof. Dr.


Professor of Neurophysiology, Director at the Max Planck Institute for Experimental Medicine
- 1978 - 1980 PhD work with Dr. F. Conti in Camogli, Italy
- 1980 - 1983 Post Doc in the Department of Physiology and Biophysics in Seattle, USA, with Dr. W. Almers
- 1983 - 1992 Group leader at the Max Planck Institute for Biophysical Chemistry in Göttingen with Dr. E. Neher
- 1992 - present Director of the Department Molecular Biology of Neuronal Signals at the Max Planck Institute for Experimental Medicine in Göttingen

Major Research Interests
The principal aim of the department "Molecular Biology of Neuronal Signals" is the study of signaling within cells and between cells. To this end, molecular biology, genetics and electrophysiology are used to elucidate structure-function relationships of membrane-bound proteins, expecially ion channels and receptors. Specific tools such as antibodies and toxins are developed and used to interfere with signaling pathways relevant for cell cycle control, ion selectivity and the secretion of cells in culture and in primary cells.

Homepage Department/Research Group:
http://www.em.mpg.de/index.php?id=60&no_cache=1

Selected Recent Publications

  • Martin S, Lino de Oliveira C, Mello de Queiroz F, Pardo LA, Stühmer W, and Del Bel E (2008) Eag1 potassium channel immunohistochemistry in the CNS of adult rat and selected regions of human brain. Neuroscience 155, 833-844

  • Downie BR, Sánchez A, Knötgen H, Contreras-Jurado C, Gymnopoulos M, Weber C, Stühmer W, and Pardo LA (2008) Eag1 expression interferes with hypoxia homeostasis and induces angiogenesis in tumors. J. Biol. Chem. 283, 36234-36240

  • Alves F, Dullin C, Napp J, Missbach-Guentner J, Jannasch K, Mathejczyk J, Pardo LA, Stühmer W, and Tietze L-F (2009) Concept of a selective tumour therapy and its evaluation by near-infrared flurorescence imaging and flat-panel volume computed tomography in mice. Eur. J. Radiology 70, 286-293

  • Gómez-Varela, D., Kohl, T., Schmidt, M., Rubio, M.E., Kawabe, H., Nehring, R., Schäfer, S., Stühmer, W. and Pardo, L. (2010) Characterization of Eag1 channel lateral mobility in rat hippocampal cultures by single-particle-tracking with quantum dots. PLoS ONE 5, e8858

  • Gonçalves, J.T. and Stühmer, W. (2010) Calmodulin interaction with hEAG1 visualized by FRET microscopy. PLoS ONE 5(5): e10873




  • GGNB Stuehmer

    Address
    Prof. Dr. Walter Stühmer
    Dept. of Molecular Biology of Neuronal Signals
    Max Planck Institute for Experimental Medicine
    Hermann-Rein-Str. 3
    37075 Göttingen
    Germany
    Tel.: +49-(0)551-3899 646
    Fax: +49-(0)551-3899 644
    e-mail: ws@em.mpg.de

    GGNB Affiliation
    Neurosciences (IMPRS)
    Molecular Physiology of the Brain (C
    MPB)