Graduated in January 2010


Doctoral Thesis
Synthesis, organisation and structural studies of peptide motifs interacting with membrane systems


Doctoral Thesis Committee

• Diederichsen, Ulf, Prof. Dr. - Organic and Biomolecular Chemistry (Uni-Che)


• Steinem, Claudia, Prof. Dr. - Organic and Biomolecular Chemistry (Uni-Che)


• Salditt, Tim, Prof. Dr. - X-Ray Physics (Uni-Phy)

University Education

• 07/2006-01/2010 University of Göttingen / GGNB program Physics of Biological and Complex Systems


• 10/2003-06/2006 Georg August University Göttingen, Germany, Diplom, Chemistry, thesis: "Synthese von Peptidhelices zur Organisation in Lipidmembranen"


• 10/2001-09/2003 Humboldt University Berlin, Germany, Vordiplom, Chemistry

Publications

• Schneggenburger PE, Beerlink A, Weinhausen B, Salditt T, Diederichsen U. Peptide model helices in lipid membranes: insertion, positioning, and lipid response on aggregation studied by X-ray scattering. Eur. Biophys. J. 2011 Apr;40(4):417-36.


• Schneggenburger PE, Worbs B, Diederichsen U. Azide Reduction During Peptide Cleavage from Solid Support – The Choice of Thioscavenger? J. Pept. Sci. 2010 Jan;16(1):10-4.


• Schneggenburger PE, Müllar S, Worbs B, Steinem C, Diederichsen U. Molecular Recognition at the Membrane-Water Interface: Controlling Integral Peptide Helices by Off-Membrane Nucleobase Pairing. J. Am. Chem. Soc. 2010 Jun 16;132(23):8020-8.


• Schneggenburger PE, Beerlink A, Worbs B, Salditt T, Diederichsen U. A Novel Heavy-Atom Label for Side-Specific Peptide Iodination: Synthesis, Membrane Incorporation and X-ray Reflectivity. ChemPhysChem. 2009 Jul 13;10(9-10):1567-76.


• Küsel A, Khattari Z, Schneggenburger PE, Banerjee A, Salditt T, Diederichsen U. Conformation and Interaction of a D,L-Alternating Peptide with a Bilayer Membrane: X-ray Reflectivity, CD and FTIR Spectroscopy. ChemPhysChem. 2007 Nov 12;8(16):2336-43.

Poster Presentations

• Schneggenburger PE, Küsel A, Beerlink A, Salditt T, Diederichsen U (2007) Structural Studies of D,L-Alternating Peptides Embedded in Model Membranes; 8th German Peptide Symposium, Heidelberg (Germany)


• Schneggenburger PE, Küsel A, Weiß A, Alexopoulos E, Usón I, Sheldrick GM, Diederichsen U (2005) D,L-Alternating Peptides and β-Peptides as Structural Motifs for Incorporation into Model Membranes, 1st German-French Congress in Organic Chemistry, Goslar

Talks

• Schneggenburger PE, Küsel A, Beerlink A, Salditt T, Diederichsen U (2008) Peptide Dimer Motifs of D,L-Alternating Configuration – Structural Studies and Molecular Design with Respect to Interaction and Recognition in the Membrane Environment, 2nd EuCheMS Chemistry Congress, Torino (Italy)


• Diederichsen U, Srivastava R, Schneggenburger PE (2008) Organization of Peptide Helices with Potential for Membrane Channel Formation, Akabori Conference (Japan)


• Schneggenburger PE (2006) Structural Studies of D,L-Alternating Peptides Embedded in Model Membranes; 1st European Chemistry Congress, Budapest (Hungary) (appetizer talk).