Physics of Biological and Complex Systems
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Camilo Aponte-Santamaría


Graduated in February 2011


Doctoral Thesis Project
Understanding the molecular machinery of aquaporins through molecular dynamics simulations


Doctoral Thesis Committee




University Education


  • 09/2007-02/2011 Max Planck Institute for Biophysical Chemistry / University of Göttingen / GGNB program Physics of Biological and Complex Systems

  • 08/2005-08/2007 Universidad Nacional de Colombia, Bogotá, Master, Physics, thesis: "Brownian Dynamics simulations of the rotation of the F1-ATPase molecular motor"

  • 02/2000-12/2004 Universidad Nacional de Colombia, Bogotá, Diplom, thesis: "The Gramicidin A Channel: A comparison between an elemental
    permeation model and a Brownian Dynamics simulation"



Publications


  • Hub JS, Aponte-Santamaría C, Grubmüller H, de Groot BL. Voltage-regulated water flux through aquaporin channels in silico. Biophys. J.2010 Dec 15;99(12):L97-9.

  • Aponte-Santamaría C, Hub JS, de Groot BL. Dynamics and energetics of solute permeation through the Plasmodium falciparum aquaglyceroporin. Phys Chem Chem Phys. 2010 Sep 21;12(35):10246-54.

  • Wolf MG, Hoefling M, Aponte-Santamaría C, Grubmüller H, Groenhof G. g_membed: Efficient insertion of a membrane protein into an equilibriated lipid bilayer with minimal perturbation. J. Comp.Chem. 2010 Aug;31(11):2169-74.

  • Fischer G, Kosinska-Eriksson U, Aponte-Santamaría C, Palmgren M, Geijer C, Hedfalk K, Hohmann S, de Groot BL, Neutze R, Lindkvist-Petersson K. Crystal Structure of a Yeast Aquaporin at 1.15 Angstrom Reveals a Novel Gating Mechanism. PLoS Biology. 2009 Jun;7(6):e1000130.



Talks

  • 06/2010: "Dynamics and energetics of the solute permeation through the Plasmodium falciparum malaria aquaglyceroporin", International Workshop on Epithelial Transport, 25-27 June 2010, Austria.

  • 02/2010: "The Gating Mechanism of Yeast Aquaporin Studied by Molecular Dynamics Simulations" 54th annual meeting of the biophysical society, San Francisco.





  • GGNB_Students_Aponte,Camilo

    Camilo Aponte-Santamaría

    from Colombia

    PhD alumnus in de Groot lab