Doctoral Thesis Project
Inhibitor Design Targeted at Specific Membrane Proteins


Doctoral Thesis Committee

• de Groot, Bert, Dr. - Computational Biomolecular Dynamics (MPI-bpc)


• Enderlein, Jörg Prof. Dr. - Biophysics / Complex Systems (Uni-Phy)


• Stark, Holger, Prof. Dr. - 3-D Cryo Electron Microscopy (MPI-bpc)

Homepage Department/Research Group

http://www.mpibpc.mpg.de/groups/de_groot/



University Education

• 01/2009-present Max Planck Institute for Biophysical Chemistry / University of Göttingen / GGNB program Physics of Biological and Complex Systems


• 10/2006-12/2008 Georg August University, Göttingen, Germany, Diplom, Physics, thesis: "Molecular Dynamics Study Of Potassium Channels, Their Interaction With Non-Amino Acid Compounds And Peptidic Scorpion Toxins"


• 10/2002-10/2006 Leibniz University; Hannover, Germany, Vordiplom, Physics

Publications

• Stary A, Wacker SJ, Boukharta L, Zachariae U, Karimi-Nejad Y, Aqvist J, Vriend G, de Groot BL. Toward a consensus model of the hERG potassium channel. ChemMedChem. 2010 Mar 1;5(3):455-67.


• Zachariae U, Schneider R, Velisetty P, Lange A, Seeliger D, Wacker SJ, Karimi-Nejad Y, Vriend G, Becker S, Pongs O, Baldus M, de Groot BL. The molecular mechanism of toxin-induced conformational changes in a potassium channel:relation to c-type inactivation. Structure. 2008 May;16(5):747-54.