Department of Psychiatry and Psychotherapy, Centre for Translational Research in Systems Neuroscience and Psychiatry
University Medical Center
- Translational Neuroimaging: Identification of neurofunctional endophenotypes of schizophrenic and affective disorders; Development of neuroimaging biomarkers for differential diagnosis and optimization of treatment strategies
- Genomic and Epigenomic Neuroimaging: Neurofunctional endophenotype-based genetic and epigenetic association studies in schizophrenic and affective disorders
- Systems Neuroscience and Clinical Neuroimaging: Affective, Cognitive, and Social Neuroscience, Pathomechanisms of schizophrenic and affective disorders in dynamically interacting key neural systems
Education and Employment
|2007 -||Professor of Systems Neuroscience and Psychiatry, Deputy Chairman and Assistant Medical Director, Head of the Centre for Translational Research in Systems Neuroscience and Clinical Psychiatry, Department of Psychiatry and Psychotherapy, Georg August University Göttingen, Germany|
|2006||Habilitation, Psychiatry and Psychotherapy, Saarland University, Homburg, Germany|
|2004 - 2007||Junior Professor of Cognitive Neuroscience in Psychiatry, Specialist Registrar, Department of Psychiatry and Psychotherapy, Saarland University, Homburg, Germany|
|2004 - 2006||Acting Director, Dept. of Medical and Clinical Psychology, Saarland University, Homburg, Germany|
|2003 - 2004||Group Leader and Head of Neuroimaging Lab, Dept. of Psychiatry and Psychotherapy, Saarland University, Homburg, Germany|
|2001 - 2003||Assistant Doctor and Postdoctoral Fellow, Dept. of Psychiatry III, University of Ulm, Germany|
|2001 - 2005||Research Associate, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany|
|1999||Dr. med., Medicine, Psychiatry, J. W. Goethe University Frankfurt, Germany|
|1998 - 2001||Assistant Doctor and Postdoctoral Research Fellow, Max Planck Institute of Cognitive and Brain Sciences, Leipzig, Day-care Clinic for Cognitive Neurology, University of Leipzig, Germany|
|1997 - 1998||Assistant Doctor and Postdoctoral Research Fellow, Dept. of Neurology, Heinrich Heine University Düsseldorf, and Institute of Medicine at Research Center Jülich, Germany|
|1995 - 1996||Resident, Department of Psychiatry and Psychotherapy, Friedrich Wilhelm University, Bonn, Germany|
|1995||State examination, Medicine (M. D.), J. W. Goethe University Frankfurt and J. Liebig University Giessen, Germany|
|1988 - 1994||University studies of Medicine, Psychology, Philosophy and Biological Anthropology, J. W. Goethe University Frankfurt, Germany|
Selected honours and awards
|2008||Essex Pharma Research Award|
|2008||Research Award, German Society of Biological Psychiatry|
|2008||Poster Award, Three-Countries-Symposium for Biological Psychiatry|
|2007||Travel Award, Organization for Human Brain Mapping (senior author)|
|2006||Best Poster Award, International Society for Bipolar Disorders|
|2006||Travel Award, Organization for Human Brain Mapping (senior author)|
|2005||WFSBP Poster Award (World Congress of Biological Psychiatry)|
|2005||Travel Award, Organization for Human Brain Mapping (senior author)|
Diekhof, E.K. & Gruber, O. (2010) When desire collides with reason: functional interactions between anteroventral prefrontal cortex and nucleus accumbens underlie the human ability to resist impulsive desires. Journal of Neuroscience, 30 (4), 1488-1493.
Gruber, O., Tost, H., Henseler, I., Schmael, C., Scherk, H., Ende, G., Ruf, M., Falkai, P., & Rietschel, M. (2010) Pathological amygdala activation during working memory performance: evidence for a pathophysiological trait marker in bipolar affective disorder. Human Brain Mapping, 31:115-125.
Pajonk, F.G., Wobrock, T., Gruber, O., Scherk, H., Berner, D., Kaizl, I., Kierer, A., Müller, S., Oest, M., Meyer, T., Backens, M., Schneider-Axmann, T., Thornton, A.E., Honer, W.G. & Falkai, P. (2010) Hippocampal plasticity in response to exercise in schizophrenia. Archives of General Psychiatry, 67(2), 133-143.
Gruber, O. & von Cramon, D. Y. (2003) The functional neuroanatomy of human working memory revisited – evidence from 3T-fMRI studies using classical domain-specific interference tasks. NeuroImage, 19:797-809.
Gruber, O., Indefrey, P., Steinmetz, H. & Kleinschmidt, A. (2001) Dissociating neural correlates of cognitive components in mental calculation. Cerebral Cortex, 11:350-359.