Stühmer, Walter, Prof. Dr.

Professor of Neurophysiology, Director at the Max Planck Institute for Experimental Medicine

  • 1978 - 1980: PhD work with Dr. F. Conti in Camogli, Italy
  • 1980 - 1983: Post Doc in the Department of Physiology and Biophysics in Seattle, USA, with Dr. W. Almers
  • 1983 - 1992: Group leader at the Max Planck Institute for Biophysical Chemistry in Göttingen with Dr. E. Neher
  • 1992 - present: Director of the Department Molecular Biology of Neuronal Signals at the Max Planck Institute for Experimental Medicine in Göttingen

  • Major Research Interests

    The principal aim of the department "Molecular Biology of Neuronal Signals" is the study of signaling within cells and between cells. To this end, molecular biology, genetics and electrophysiology are used to elucidate structure-function relationships of membrane-bound proteins, expecially ion channels and receptors. Specific tools such as antibodies and toxins are developed and used to interfere with signaling pathways relevant for cell cycle control, ion selectivity and the secretion of cells in culture and in primary cells.

    Homepage Department/Research Group:

    Selected Recent Publications

  • Lazzarini, M., Martin, S., Mitkovski, M., Vozari, R.R., Stühmer, W. and Del Bel, E. (2013) Doxycycline restrains glia and confers neuroproteciotn in a 6-OHDA Parkinson model. Glia 61, 1084-1100. Doi: 10.1002/glia.22496
  • El Hady, A., Afshar, G., Broeking, K., Schlüter, O., Geisel, T., Stühmer, W. and Wolf, F. (2013) Optogenetic stimulation effectively enhances intrinsically generated network synchrony. Frontiers in Neural Circuits 7, 167. Doi: 10.3389/fncir.2013.00167
  • Issy, A.C., Fonseca, J.R., Pardo, L.A., Stühmer, W. and Del Bel, E. (2014) Hippocampal ether-à-go-go-1 potassium channels blockade: Effects in the startle reflex and prepulse inhibition. Neurosci. Lett. 559, 13-17. Doi: 10.1016/j.neulet.2013.11.026
  • Urrego Blanco, D., Tomczak, A., Zahed, F., Stühmer, W. and Pardo, L.A. (2014) Potassium channels in cell cycle and cell proliferation. Phil. Trans¬. Royal Soc. B. 369. Doi: 10.1098/rstb.2013.0094
  • Pardo, L.A. and Stühmer, W. (2014) The roles of K+ channels in cancer. Nat. Rev. Cancer 14, 39-48. Doi: 10.1038/nrc3635