Institute of Organic and Biomolecular Chemistry

Research Topics: Chemical Biology and Peptide Design

Design, synthesis and characterisation of small protein folding motifs with focus on the coiled-coil motif and the WW domain. Application of the de novo designed peptide components in the design of small functional peptide devices.


  • De novo design and redesign of small protein folding motifs

  • Structural analysis with biophysical methods such as CD spectroscopy, NMR spectroscopy and analytical ultracentrifugation

  • Organic synthesis of linkers and non-proteinogenic amino acids

  • Application of designed peptide building blocks as templates for chemical reactions, as catalysts and as association tools in the synthesis of molecular libraries






For more information please visit the homepage of Dr. Franziska Thomas.




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