Institute of Organic and Biomolecular Chemistry

Research Area: Biomolecular Chemistry

Functional nucleic acids in organic and biomolecular chemistry for labeling, detection and visualization of biomolecules.

  • Structural and mechanistic analysis of nucleic acid catalysis (ribozymes and deoxyribozymes)
  • In-vitro selection of fluorogenic RNA / DNA aptamers and deoxyribozymes
  • RNA labeling with deoxyribozymes using DNA-catalyzed ligation chemistry
  • Synthesis of paramagnetic nucleoside building blocks for EPR spectroscopy
  • Detection of natural modified nucleosides by fluorogenic bioorthogonal labeling

For further information, see homepage of Prof. Höbartner or Max-Planck-Institute for Biophysical Chemistry.

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