Göttingen Graduate School for Neurosciences, Biophysics, and Molecular Biosciences
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Jäckle, Herbert, Prof. Dr.


Professor, Director at the Max Planck Institute for Biophysical Chemistry


  • Faculty member, EMBL, Heidelberg

  • Head of research group, MPI for Developmental Biology, Tübingen

  • Professor and Chairman, Dept of Genetics and Microbiology, LMU Munich

  • Director, Dept of Molecular Developmental Biology, MPI for Biophysical Chemistry, Göttingen

  • Vice-President of the Max Planck Society




Major Research Interests

Our research interest is focused on molecular processes and the mechanisms involved in the phenonenon of biological pattern formation during Drosophila embryogenesis. Aim of my studies is a better understanding of the biochemical pathways and the molecular characterization of the regulatory networks leading to the establishment of the segmental organization of the embryo, organ formation and cell behaviour underlying morphogenesis. Recent work concerns the genetic basis for energy homeostasis in cells.


Homepage Department/Research Group

http://www.mpibpc.mpg.de/groups/jaeckle/



Selected Recent Publications


  • Beller M, Bulankina AV, Hsiao HH, Urlaub H, Jäckle H, et al. (2010) PERILIPIN-Dependent Control of Lipid Droplet Structure and Fat Storage in Drosophila. Cell Metabolism 12: 521-532

  • Günesdogan U, Jäckle H, Herzig A (2010) A genetic system to assess in vivo the functions of histones and histone modifications in higher eukaryotes. EMBO Rep 11: 772-776

  • Löhr U, Chung HR, Beller M, Jäckle H (2009) Antagonistic action of Bicoid and the repressor Capicua determines the spatial limits of Drosophila head gene expression domains. Proc Nat Acad Sci USA 106: 21695-21700

  • Karpinar DP, Balija MBG, Kugler S, Opazo F, Rezaei-Ghaleh N, Wender N, Kim HY, Taschenberger G, Falkenburger BH, Heise H, Kumar A, Riedel D, Fichtner L, Voigt A, Braus GH, Giller K, Becker S, Herzig A, Baldus M, Jäckle H, Eimer S, Schulz JB, Griesinger C, Zweckstetter M (2009) Pre-fibrillar alpha-synuclein variants with impaired beta-structure increase neurotoxicity in Parkinson's disease models. EMBO J 28: 3256-3268

  • Chanana B, Steigemann P, Jäckle H, Vorbrüggen G (2009) Reception of Slit requires only the chondroitin sulphate-modified extracellular domain of Syndecan at the target cell surface. Proc Nat Acad Sci USA 106: 11984-1198








GGNB Jaeckle

Address
Prof. Dr. Herbert Jäckle
Max Planck Institute
for Biophysical Chemistry
Dept. of Molecular Developmental Biology
Am Fassberg 11
37077 Göttingen
Germany

Tel.: +49-(0)551-201 1482
Fax: +49-(0)551-201 1755
e-mail: hjaeckl@gwdg.de

GGNB Affiliation
Molecular Biology (IMPRS)
Genes and Development