Research Group of Prof. Dr. Claudia Steinem


2017 - 2016 - 2015 - 2014 - 2013 - 2012 - 2011 - 2010 - 2009 - 2008 - 2007 - 2006 - 2005 - 2004 - 2003 - 2002 - 2001 - 2000 - 1999 - 1998 - 1997 - 1996


Schütte, O.M., Mey, I., Enderlein, J., Savic, F., Geil, B., Janshoff, A., Steinem, C., Size and mobility of lipid domains tuned by geometrical constraints, 2017, Proc. Natl. Acad. Sci. U. S. A., online, DOI: 10.1073/pnas.1704199114.

Schwamborn, M., Schumacher, J., Sibold, J., Teiwes, N.K., Steinem, C. (2017) Monitoring ATPase induced pH changes in single proteoliposomes with the lipid-coupled fluorophore Oregon Green 488. Analyst. DOI: 10.1039/C7AN00215G.

Kuhlmann, J.W., Junius, M., Diederichsen, U., Steinem, C. (2017) SNARE-Mediated Single-Vesicle Fusion Events with Supported and Freestanding Lipid Membranes. Biophys. J. 112, 2348-2356. DOI: 10.1016/j.bpj.2017.04.032 .


Gräb, O., Abacilar, M., Daus, F., Geyer, A., Steinem, C. (2016) 3D-Membrane stacks on supported membranes composed of diatom lipids induced by long-chain polyamines. Langmuir 32, 10144-10152. DOI: 10.1021/acs.langmuir.6b02575.

Gleisner, M., Kroppen, B., Fricke, C., Teske, N., Kliesch, T.-T., Janshoff, A., Meinecke, M., Steinem, C. (2016) Epsin N-terminal homology domain (ENTH) activity as a function of membrane tension. J. Biol. Chem. 291, 19953-19961. DOI: 10.1074/jbc.M116.731612.

Briones, T., Weichbrodt, C., Paltrinieri, L., Mey, I., Villinger, S., Giller, K., Lange, A., Zweckstetter, M., Griesinger, C., Becker, S., Steinem, C., de Groot, B.L. (2016) Voltage-dependence of conformational dynamics and subconducting states of VDAC-1. Biophys. J. 111, 1223-1234. DOI: 10.1016/j.bpj.2016.08.007.

Shabardina, V., Kramer, C., Gerdes, B., Braunger, J., Cordes, A., Schäfer, J., Mey, I., Grill, D., Gerke, V., Steinem, C. (2016) Mode of ezrin-membrane interaction as a function of PIP2 binding and pseudophosphorylation. Biophys. J. 110, 2710-2719. DOI: 10.1016/j.bpj.2016.05.009.

Rost, U., Steinem, C., Diederichsen, U. (2016) beta-Glutamine-mediated self-association of transmembrane beta-peptides within lipid bilayers. Chem. Sci. 7, 5900-5907. DOI: 10.1039/C6SC01147K.

Kumar, Y. P., Das, R. N., Schütte, O. M., Steinem, C., Dash, J. (2016) Bis-triazolyl diguanosine derivatives as synthetic transmembrane ion channels. Nat. Protocols 11, 1039-1056. DOI: 10.1038/nprot.2016.045 .

Ludolphs, M., Schneeberger, D., Soykan, T., Schäfer, J., Papadopoulos, T., Brose, N., Schindelin, H., Steinem, C. (2016) Specificity of collybistin-phosphoinositide interactions: Impact of the individual protein domains. J. Biol. Chem. 291, 244-254. DOI: 10.1074/jbc.M115.673400.


Schwenen, L.L.G., Hubrich, R., Milovanovic, D., Geil, B., Yang, J., Kros, A., Jahn, R., Steinem, C. (2015) Resolving single membrane fusion events on planar pore-spanning membranes. Sci. Rep. 5, 12006. DOI: 10.1038/srep12006.

Steinem, C., Bill, J. (2015) Towards multifunctional inorganic materials: biopolymeric templates. Beilstein J. Nanotechnol. 6, 1698-1699. DOI: 10.3762/bjnano.6.172.

Schütte, O.M., Patalag, L.J., Weber, L.M.C., Ries, A., Römer, W. Werz, D.B., Steinem, C. (2015) 2-Hydroxy fatty acid enantiomers of Gb3 glycosphingolipids impact Shiga toxin binding and membrane organization. Biophys. J. 108, 2775-2778. DOI: 10.1016/j.bpj.2015.05.009 .
see also: N&N, Eghiaian, F. (2015) Lipid chirality revisited: A change in lipid configuration transforms membrane-bound protein domains. Biophys. J. 108, 2757-2758. DOI: 10.1016/j.bpj.2015.05.018 .

Janshoff, A., Steinem, C. (2015) Mechanics of lipid bilayers: What do we learn from pore-spanning membranes? Biochim. Biophys. Acta, Mol. Cell Res. 1853, 2977-2983. DOI: 10.1016/j.bbamcr.2015.05.029 .

Ries, O., Carnarius, C., Steinem, C., Ducho, C. (2015) Membrane-interacting properties of the functionalised fatty acid moiety of muraymycin antibiotics. Med. Chem. Comm. 6, 879-886. DOI: 10.1039/C4MD00526K .

Das, R. N., Kumar, P., Schütte, O. M., Steinem, C., Dash, J. (2015) A DNA-inspired synthetic ion channel based on G-C base pairing. J. Am. Chem. Soc. 137, 34-37. DOI: 10.1021/ja510470b .

Kaufeld, T., Steinem, C., Schmidt, C. (2015) Microporous device for local electric recordings on model lipid bilayers. J. Phys. D: Appl. Phys. 48, 025401. DOI: 10.1088/0022-3727/48/2/025401 .


Gleisner, M. Mey, I., Barbot, M., Dreker, C., Meinecke, M., Steinem, C. (2014) Driving a planar model system into the 3rd dimension: Generation and control of curved pore-spanning membrane arrays. Soft Matter 10, 6228-6236. DOI: 10.1039/C4SM00702F .

Kuhlmann, J.W., Mey, I.P., Steinem, C. (2014) Modulating the lateral tension of solvent-free pore-spanning membranes. Langmuir 30, 8186-8192. DOI: 10.1021/la5019086 .

Schütte, O.M. Ries, A., Orth, A., Patalag, L.K., Römer, W., Steinem, C., Werz, D.B. (2014) Influence of Gb3 glycosphingolipids differing in their fatty acid chain on the phase behavior of solid supported membranes: Chemical syntheses and impact of Shiga toxin binding. Chem. Sci. 5, 3104-3114. DOI: 10.1039/C4SC01290A .

Braunger, J. A., Brückner, B. R., Nehls, S., Pietuch, A., Gerke, V. Mey, I., Janshoff, A., Steinem, C. (2014) Phosphatidylinositol 4,5-bisphosphate alters the number of attachment sites between ezrin and actin filaments: a colloidal probe study. J. Biol. Chem. 289, 9833-9843. DOI: 10.1074/jbc.M113.530659 .

Neubacher, H., Carnarius, C., Mey, I., Lazzara, T. D., Steinem, C. (2014) Permeabilization assay for antimicrobial peptides based on pore-spanning lipid membranes on nanoporous alumina. Langmuir 30, 4767-4774. DOI: 10.1021/la500358h .

Hafi, N., Grunwald, M., van den Heuvel, L. S., Aspelmeier, T., Chen, J.-H., Zagrebelsky, M., Schütte, O. M., Steinem, C., Korte, M., Munk, A., Walla, P. J. (2014) Fluorescence nanoscopy by polarization modulation and polarization angle narrowing. Nat. Methods 11, 579-584. DOI: 10.1038/nmeth.2919 .
see also: Reply, Hafi, N., Grunwald, M., van den Heuvel, L. S., Aspelmeier, T., Chen, J.-H., Zagrebelsky, M., Schütte, O. M., Steinem, C., Korte, M., Munk, A., Walla, P. J. (2015) Polarization modulation adds little additional information to super-resolution fluorescence microscopy. Nat. Methods 13, 8-9. DOI: 10.1038/nmeth0116-101a .

Kozuch, J., Weichbrodt, C., Millo, D., Becker, S., Giller, K., Hildebrandt, P., Steinem, C. (2014) Voltage-dependent structural changes of the membrane-bound anion channel hVDAC1 probed by SEIRA and electrochemical impedance spectroscopy. Phys. Chem. Chem. Phys. 16, 9546-9555. DOI: 10.1039/C4CP00167B .

Kumar, Y. P., Das, R. N., Kumar, S., Schütte, O. M., Steinem, C., Dash, J. (2014) Triazole tailored guanosine dinucleosides as biomimetic ion channels to modulate transmembrane potential. Chem. Eur. J. 20, 3023-3028. DOI: 10.1002/chem.201304530 .

Stephan, M., Kramer, C., Steinem, C., Janshoff, A. (2014) Binding assay for low molecular weight analytes based on reflectometry of absorbing molecules in porous substrates. Analyst 139, 1987-1992. DOI: 10.1039/C4AN00009A .

Stephan, M., Mey, I., Steinem, C., Janshoff, A. (2014) Combining reflectometry and fluorescence microscopy: An assay for the investigation of leakage processes across lipid membranes. Anal. Chem. 86, 1366-1371. DOI: 10.1021/ac4020726 .

Lazzara, T.D., Janshoff, A., Steinem, C. (2014) Biofunctionalization of nanoporous alumina substrates in Handbook of Nanomaterials Properties. Springer, pp 911-940. ISBN: 978-3-642-31107-9 .


Braunger, J. A., Kramer, C., Morick, D., Steinem, C. (2013) Solid supported membranes doped with PIP2 - influence of ionic strength and pH on bilayer formation and membrane organization. Langmuir 29, 14204-14213. DOI: 10.1021/la402646k .

Hotz, T., Schütte, O. M., Sieling, H., Polupanow, T., Diederichsen, U., Steinem, C., Munk, A. (2013) Idealizing ion channel recordings by a jump segmentation multiresolution filter. IEEE Transact. NanoBiosci. 12, 376-386. DOI: 10.1109/TNB.2013.2284063 .

Steinem, C. (2013) Funktionelle Lipidmembranen in der Chiptechnologie. Nachrichten aus der Chemie 61, 1101-1104. DOI: 10.1002/nadc.201390357 .

Frese, D., Steltenkamp, S., Schmitz, S., Steinem, C. (2013) In situ generation of electrochemical gradients across pore-spanning membranes. RSC Adv. 3, 15752-15761. DOI: 10.1039/C3RA42723D .

Behn, D., Schatz, M., Hubrich, R., Hoffmeister, H., Krefft, A., Witzgall, R., Steinem, C. (2013) Phosphorylation of C-terminal polycystin-2 influences the interaction with PIGEA14: A QCM study based on solid supported membranes. Biochim. Biophys. Res. Comm. 437, 532-537. DOI: 10.1016/j.bbrc.2013.06.105 .

Song, C., Weichbrodt, C., Salnikovc, E.S., Dynowskid, M., Forsberg, B.O., Bechinger, B., Steinem, C., de Groot, B.L., Zachariae, U., Zeth, K. (2013) Crystal structure and functional mechanism of a human antimicrobial membrane channel. Proc. Natl. Acad. Sci. U.S.A. 110, 4586-4591. DOI: 10.1073/pnas.1214739110 .

Weiher, F., Schatz, M., Steinem, C., Geyer, A. (2013) Silica precipitation by synthetic minicollagens. Biomacromolecules 14, 683-687. DOI: 10.1021/bm301737m .


Kozuch, J., Steinem, C., Hildebrandt, P. Millo, D. (2012) Combined electrochemistry and surface-enhanced infrared absorption spectroscopy of gramicidin A incorporated into tethered bilayer lipid membranes. Angew. Chem. Int. Ed. 51, 8114-8117. DOI: 10.1002/anie.201203214 .

Lazzara, T.D., Lau, K.H.A., Knoll, W., Janshoff, A., Steinem, C. (2012) Macromolecular shape and interactions in layer-by-layer assemblies within cylindrical nanopores. Beilstein. J. Nanotechnol. 3, 475-484. DOI: 10.3762/bjnano.3.54 .

Mey, I., Steinem, C., Janshoff, A. (2012) Biomimetic functionalization of porous substrates: towards model systems for cellular membranes. J. Mater. Sci. 22, 19348-19356. DOI: 10.1039/C2JM31737K .

Carnarius, C., Kreir, M., Krick, M., Methfessel, C., Moehrle, V., Valerius, O., Brüggemann, A., Steinem, C., Fertig, N. (2012) Green fluorescent protein changes the conductance of connexin 43 (Cx43) hemichannels reconstituted in planar lipid bilayers. J. Biol. Chem. 287, 2877-2886. DOI: 10.1074/jbc.M111.319871 .

Orth, A., Johannes, L., Römer, W., Steinem, C. (2012) Creating and modulating microdomains in pore-spanning membranes. ChemPhysChem 13, 108-114. DOI: 10.1002/cphc.201100644 .

Janshoff, A., Steinem, C. (2012) Supported lipid bilayers: intelligent surfaces for ion channel recordings in Intelligent Surfaces: Polymer coatings for applications in bio‐related and life sciences, Textor, M (Editor), John Wiley and Sons, Inc., pp 141-182. ISBN: 978-0-470-53650-6 .

Lazzara, T. D., Behn, D., Kliesch, T.-T., Janshoff, A., Steinem, C. (2012) Phospholipids as an alternative to direct covalent coupling: Functionalization of nanoporous alumina for protein recognition and purification. J. Coll. Inter. Sci. 366, 57-63. DOI: 10.1016/j.jcis.2011.09.067 .

Michaelis, S. Rommel, C.E., Endell, J., Göring, P., Wehrspohn, R., Steinem, C., Janshoff, A., Galla, H.,-J, Wegener, J. (2012) Macroporous silicon chips for laterally resolved, multi-parametric analysis of epithelial barrier function. Lab Chip 12, 2329-2336. DOI: 10.1039/C2LC00026A .


Lazzara, T. D., Carnarius, C., Kocun, M., Janshoff, A., Steinem, C. (2011) Separating attoliter-sized compartments using fluid pore-spanning lipid bilayers. ACS Nano 5, 6935-6944. DOI: 10.1021/nn201266.

Boll, A., Jatho, A., Czudnochowski, N., Geyer, M., Steinem, C. (2011) Mechanistic insights into the translocation of full length HIV-1 Tat across lipid membranes. Biochim. Biophys. Acta - Biomembranes 1808, 2685-2693. DOI: 10.1016/j.bbamem.2011.07.030.

Wieneke, R., Bernecker, A., Riedel, R., Sumper, M., Steinem, C., Geyer, A. (2011) Silica precipitation with synthetic silaffin peptides. Org. Biomol. Chem. 9, 5482-5486. DOI: 10.1039/C1OB05406F .

Lazzara, T. D., Mey, I., Steinem, C., Janshoff, A. (2011) Benefits and limitations of porous substrates as biosensors for protein adsorption. Anal. Chem. 83, 5624-5630. DOI: 10.1021/ac200725y .

Kocun, M., Lazzara, T. D., Steinem, C., Janshoff, A. (2011) Preparation of solvent-free, pore-spanning lipid bilayers: modeling the low tension of plasma membranes. Langmuir 27, 7672-7680. DOI: 10.1021/la2003172.

Lazzara, T. D., Kliesch, T.-T., Janshoff, A., Steinem, C. (2011) Orthogonal functionalization of nanoporous substrates: control of 3D surface functionality. ACS Appl. Mater. Interfaces 3, 1068-1076. DOI: 10.1021/am101212h.

Bosk, S., Braunger, J., Gerke, V., Steinem, C. (2011) Activation of F-actin binding capacity of ezrin: synergism of PIP2 interaction and phosphorylation. Biophys. J. 100, 1708-1717. DOI: 10.1016/j.bpj.2011.02.039.

Höfer, I., Steinem, C. (2011) A membrane fusion assay based on pore-spanning membranes. Soft Matter 7, 1644-1647. DOI: 10.1016/j.bpj.2009.12.3695.

Schmitt, E.K., Steinem, C. (2011) Electrochemical analysis of ion channels and transporters in pore-suspending membranes in Modern Aspects in Electrochemistry, Springer. DOI: 10.1007/978-1-4614-2137-5_5.


Steinem., C., Janshoff, A. (2010) Multicomponent membranes on solid substrates: Interfaces for protein binding. Curr. Op. Coll. Interf. Sci. 15, 479-488. DOI: 10.1016/j.cocis.2010.06.004.

Bernecker, A., Ziomkowska, J., Heitmüller, S., Wieneke, R., Geyer, A., Steinem, C. (2010) Formation of silica precipitates on membranes in two and three dimensions. Langmuir 26, 13422-13428. DOI: 10.1021/la1021627.

Ambrosi, C., Gaßmann, O., Pranskevich, J.N., Boassa, D., Smock, A., Wang, J., Dahl, G., Steinem, C., Sosinsky, G.E. (2010) Pannexin1 and Pannexin2 channels show quaternary similarities to connexons and different oligomerization numbers from each other. J. Biol. Chem. 285, 24420-24431. DOI: 10.1074/jbc.M110.115444.

Fritz, K., Fritz, G., Windschiegl, B., Steinem, C., Nickel, B. (2010) Arrangement of annexin A2 tetramer and its impact on the structure and diffusivity of supported lipid bilayers. Soft Matter 6, 4084-4094. DOI: 10.1039/C0SM00047G.

Janshoff, A., Lorenz, B., Pietuch, A., Fine, T., Tarantola, M., Steinem, C., Wegener, J. (2010) Cell adhesion on ordered pores: consequences for cellular elasticity. J. Adh. Sci. Technol. 24, 2287-2230. DOI: 10.1163/016942410X508028.

Schneggenburger, P.E., Müllar, S., Worbs, B., Steinem, C., Diederichsen, U. (2010) Molecular recognition at the membrane-water interface: controlling integral peptide helices by off-membrane nucleobase pairing. J. Am. Chem. Soc. 132, 8020-8028. DOI: 10.1021/ja1006349.

Kocun, M., Mueller, W., Maskos, M., Mey, I., Geil, B., Steinem, C., Janshoff, A. (2010) Viscoelasticity of pore-spanning polymer membranes derived from giant polymersoms. Soft Matter 6, 2508-2516. DOI: 10.1039/B924650A.

Behn, D., Bosk, S., Hoffmeister, H., Janshoff, A., Witzgall, R., Steinem, C. (2010) Quantifying the interaction of the C-terminal regions of polycystin-2 and polycystin-1 attached to a lipid bilayer by means of QCM. Biophys. Chem. 150, 47-53. DOI: 10.1016/j.bpc.2010.02.005.

Bernecker, A., Wieneke, R., Riedel, R., Seibt, M., Geyer, A., Steinem, C. (2010) Tailored synthetic polyamines for controlled biomimetic silica formation. J. Am. Chem. Soc. 132, 1023-1031. DOI: 10.1021/ja9061163.


Windschiegl, B., Orth, A., Römer, W., Berland, L., Stechmann, B., Bassereau, P., Johannes, L., Steinem, C. (2009) Lipid reorganization induced by shiga toxin clustering on planar membranes. PLoS ONE 4, e6238. DOI: 10.1371/journal.pone.0006238.

Schmitt, E. K., Weichbrodt, C., Steinem, C. (2009) Impedance analysis of gramicidin D in pore-suspending membranes. Soft Matter 5, 3347-3353. DOI: 10.1039/B901683J.

Mey, I., Stephan, M., Schmitt, E.K., Müller, M. M., Amar, M., B., Steinem, C., Janshoff, A. (2009) Local membrane mechanics of pore-spanning bilayers. J. Am. Chem. Soc. 131, 7031-7039. DOI: 10.1021/ja809165h.

Kepplinger, C., Höfer, I., Steinem, C. (2009) Impedance analysis of valinomycin activity in nano-BLMs. Chem. Phys. Lipids 160, 109-113. DOI: 10.1016/j.chemphyslip.2009.05.001.

Fine, T., Mey, I., Rommel, C., Wegener, J., Steinem, C., Janshoff, A. (2009) Elasticity mapping of apical cell membranes. Soft Matter 5, 3262-3265. DOI: 10.1039/B901714C.

Gaßmann, O., Kreir, M., Ambrosi, C., Pranskevich, J., Oshima, A., Röling, C., Sosinsky, G., Fertig, N., Steinem, C. (2009) The mutant of connexin26 reveals conductance states in pore-suspending membranes. J. Struct. Biol. 168, 168-176. DOI: 10.1016/j.jsb.2009.02.004.

Szilluweit, R., Boll, A., Lukowski, S., Gerlach, H., Fackler, O.T., Geyer, M., Steinem, C. (2009) HIV-1 Nef perturbs artificial membranes: investigation of the contribution of the myristoyl anchor. Biophys. J. 96, 3242-3250. DOI: 10.1016/j.bpj.2008.12.3947.

Schilling, D., Gehrmann, M., Steinem, C., De Maio, A., Pockley, A.G., Abend, M., Molls, M., Multhoff, G. (2009) Binding of heat shock protein 70 (Hsp70) to extracellular phosphatidylserine (PS) promotes killing of normoxic and hypoxic tumor cells. FASEB J. 23, 2467-2477. DOI: 10.1096/fj.08-125229.

Böcker, M., Muschter, S., Schmitt, E.K., Steinem, C., Schäffer, T.E. (2009) Imaging and patterning of pore-suspending membranes with scanning ion conductance microscopy. Langmuir 25, 3022-3028. DOI: 10.1021/la8034227.

Lorenz, B., Mey, I., Steltenkamp, S., Fine, T., Rommel, C., Müller, M.M., Maiwald, A., Wegener, J., Steinem, C., Janshoff, A. (2009) Elasticity mapping of pore suspending native membranes. Small 5, 832-838. DOI: 10.1002/smll.200800930.

Janshoff, A,. Steinem, C. (2009) Lipid membranes on highly ordered porous alumina substrates. Smart Materials, Schwartz, M. (Editor), chapter 33, pp 33-1-33-6. ISBN: 978-1-4200-4373-0.


Gehrmann, M., Liebisch, G., Schmitz, G., Anderson, R., Steinem, C., De Maio, A., Pockley, G., Multhoff, G. (2008) Tumor-specific Hsp70 plasma membrane localization is enabled by the glycosphingolipid Gb3. PLoS ONE 3, e1925. DOI: 10.1371/journal.pone.0001925.

Dhathathreyan, A., Steinem, C. (2008) Interactions of laminin peptides with phospholipids in Langmuir films and vesicles. Chem. Phys. Letters 464, 226-229. DOI: 10.1016/j.cplett.2008.09.010.

Pilz, C., Steinem, C. (2008) Modulation of the conductance of a 2,2-bipyridine-functionalized peptidic ion channel by Ni2+. Eur. Biophys. J. 37, 1065-1071. DOI: 10.1007/s00249-008-0298-8.

Janke, M., Herrig, A., Austermann, J., Gerke, V., Steinem, C., Janshoff, A. (2008) Actin binding of ezrin is activated by specific recognition of PIP2-functionalized lipid bilayers. Biochemistry 47, 3762-3769. DOI: 10.1021/bi702542s.

Vega, V. L., Rodríguez-Silva, M., Frey, T., Gehrmann, M., Diaz, J. C., Steinem, C., Multhoff, G., Arispe, N., De Maio, A. (2008) Hsp70 translocates into the plasma membrane after stress and is released into the extracellular environment in a membrane-associated form that activates macrophages. J. Immunol. 180, 4299-4307. DOI: 10.4049/jimmunol.180.6.4299 .

Faiß, S., Kastl, K., Janshoff, A., Steinem, C. (2008) Formation of irreversibly bound annexin A1 protein domains on POPC/POPS solid supported membranes. Biochim. Biophys. Acta 1778, 1601-1610. DOI: 10.1016/j.bbamem.2008.01.003.

Steinem, C., Janshoff, A. (2008) Verankert und doch mobil: Modelle biologischer Membranen auf Oberflächen. Chemie in unserer Zeit 42, 116-127. DOI: 10.1002/ciuz.200800445.

Schmitt, E.K., Nurnabi, M., Bushby, R. J., Steinem, C. (2008) Electrically insulating pore-suspending membranes on highly ordered porous alumina obtained from vesicle spreading. Soft Matter 4, 250-253. DOI: 10.1039/B716723G.

Steinem, C. (2008) Pore suspending membranes on highly ordered porous alumina and porous silicon substrates: Preparation, characterization, and application. Advances on planar lipid bilayers and liposomes, Leitmannova Liu, A. (Series Editor), chapter 3, pp 59-78. DOI: 10.1016/S1554-4516(08)00003-3.


Römer, W., Berland, L., Chambon, V., Gaus, K., Windschiegl, B., Tenza, D., Aly, M.R.E., Fraisier, V., Florent, J.-C., Perrais, D., Lamaze, C., Raposo, G., Steinem, C., Sens, P., Bassereau, P. Johannes, L. (2007) Shiga toxin induces tubular membrane invaginations for its uptake into cells. Nature 450, 670 - 675.

Faiß, S., Schuy, S., Weiskopf, D., Steinem, C., Janshoff, A. (2007) Phase transition of individually addressable microstructured membranes visualized by imaging ellipsometry. J. Phys. Chem. B 111, 13979-13986.

Weiskopf, D., Schmitt, E.K., Klühr, M. H., Dertinger, S. K., Steinem, C. (2007) Micro-BLMs on highly ordered porous silicon substrates: Rupture process and lateral mobility. Langmuir 23, 9134 -9139.

Steinem, C., Janshoff, A. (2007) Chapter 8: Specific adsorption of annexin A1 on solid supported membranes. Piezoelectric sensors, Wolfbeis, O.S. (Series Editor), Steinem, C., Janshoff, A. (Volume Editor), Springer Verlag, Berlin, ISSN 1612-7617.


Herrig, A., Janke, M., Austermann, J., Gerke, V., Janshoff, A., Steinem, C. (2006) Cooperative adsorption of ezrin on PIP2-containing membranes. Biochemistry 45, 13025-13034.

Knerr, R., Weiser, B., Drotleff, S., Steinem, C. Göpferich, A. (2006) Measuring cell adhesion on RGD-modified, self-assembled PEG monolayers using the quartz crystal microbalance technique. Macromol. Bioscience 6, 827-838.

Windschiegl, B., Steinem, C. (2006) Influence of alpha-hydroxylation of glycolipids on domain formation in lipid monolayers. Langmuir 22, 7454-7457.

Schmitt, E. K., Vrouenraets, M., Steinem, C. (2006) Channel activity of OmpF monitored in nano-BLMs. Biophys. J. 91, 2163-2171.

Steltenkamp, S., Müller, M. M., Deserno, M., Hennesthal, C., Steinem, C., Janshoff, A. (2006) Mechanical properties of pore-spanning lipid bilayers probed by atomic force microscopy. Biophys. J. 91, 217-226.

Janshoff, A., Steinem, C. (2006) Transport across artificial membranes - an analytical perspective. Anal. Bioanal. Chem. 385, 433-451.

Naarmann, N., Bilgiçer, B., Meng, H., Kumar, K., Steinem, C. (2006) Fluorinated interfaces drive self-association of transmembrane helices in lipid bilayers. Angew. Chem. 118, 2650-2653; Angew. Chem. Int. Ed. 45, 2588-2591.

Kastl, K., Menke, M., Lüthgens, E., Faiß, S., Gerke, V., Janshoff, A., Steinem, C. (2006) Partially reversible adsorption of annexin A1 on POPC/POPS bilayers investigated by QCM measurements, SFM, and DMC simulations. ChemBioChem 7, 106-115.


Menke, M., Gerke, V., Steinem, C. (2005) Phosphatidylserine membrane domain clustering induced by annexin A2/S100A10 heterotetramer. Biochemistry 44, 15296-15303.

Römer, W., Steinem, C. (2005) Lipidmembranen in Biosensoren und Arrays.

Steinem, C. (2005) Mikro- und nano-BLMS: Ein neuer Weg zu Membranbiosensoren. GIT Laborfachzeitschrift 9, 747-749.

Horn, C., Steinem, C. (2005) Photocurrents generated by bacteriorhodopsin adsorbed on nano-black lipid membranes. Biophys. J. 89, 1046-1054.

Janshoff, A., Steinem, C. (2005) Label-free detection of protein-ligand interactions by the quartz crystal microbalance. Methods in Molecular Biology: Protein-ligand interactions, Nienhaus, G. U. (Editor), pp 47-63, ISBN:1-58829-372-6.

Naarmann, N., Bilgicer, B., Kumar, K., Steinem, C. (2005) Controlling association of vesicle embedded peptides by alteration of the physical state of the lipid matrix. Biochemistry 44, 5188-5195.

Menz, B., Knerr, R., Göpferich, A., Steinem, C. (2005) Impedance and QCM analysis of the protein resistance of self assembled PEGylated alkanethiol layers on gold. Biomaterials 26, 4237-4243.

Steinem, C., Janshoff, A. (2005) Piezoelectric resonators. Encyclopedia of analytical science, Second Edition, Worsfold, P., Townshend, A., Poole, C. (Editors), pp 269-276, ISBN: 0-12-764100-9.


Römer, W., Lam, Y. H., Fischer, D., Watts, A., Fischer, W.B., Göring, P., Wehrspohn, R. B., Gösele, U., Steinem, C. (2004) Channel activity of a viral transmembrane peptide in micro-BLMs: Vpu1-32 from HIV-1. J. Am. Chem. Soc. 126, 16267-16274.

Steinem, C., Janshoff, A., Lin, V.S.-Y., Völcker, N. H., Ghadiri, M. R. (2004) DNA hybridization-enhanced porous silicon corrosion: mechanistic investigations and prospect for optical interferometric biosensing. Tetrahedron 60,11259-11267.

Janshoff, A., Steinem, C., Wegener, J. (2004) Chapter 9: Noninvasive electrical sensor devices to monitor living cells online. Ultrathin electrochemical chemo- and biosensors, Wolfbeis, O.S. (Series Editor), Mirsky, V.M. (Volume Editor), Springer Verlag, Berlin, ISSN 1612-7617.

Steinem, C., Janshoff, A. (2004) No label required: protein binding at membrane interfaces visualized through colloid phase transitions. ChemPhysChem 5, 1121-1124.

Kastl, K., Herrig, A., Lüthgens, E., Janshoff, A., Steinem, C., (2004) Scrutiny of annexin A1 mediated membrane-membrane interaction by means of a thickness shear mode resonator and computer simulations. Langmuir 20, 7246-7253.

Menke, M., Ross, M., Gerke, V., Steinem, C. (2004) The molecular arrangement of membrane-bound annexin A2-S100A10 tetramer as revealed by scanning force microscopy. ChemBioChem 5, 1003-1006.

Römer, W., Steinem, C. (2004) Impedance analysis and single-channel recordings on nano-black lipid membranes based on porous alumina. Biophys. J. 86, 955-965.


Drexler, J., Steinem, C. (2003) Pore-suspending lipid bilayers on porous alumina investigated by electrical impedance spectroscopy. J. Phys. Chem. B 107, 11245-11254.

Lüthgens, E., Herrig, A., Kastl, K., Steinem, C., Reiss, B., Wegener, J., Pignataro, B., Janshoff, A. (2003) Adhesion of liposomes: a quartz crystal microbalance study. Meas. Sci. Technol. 14, 1865-1875.

Ross, M., Gerke, V., Steinem, C. (2003) Membrane composition affects the reversibility of annexin A2t binding to solid supported membranes: a QCM study. Biochemistry 42, 3131-3141.

Reiss, B., Janshoff, A., Steinem, C., Seebach, J., Wegener, J. (2003) Adhesion kinetics of functionalized vesicles and mammalian cells: a comparative study. Langmuir 19, 1816-1823.

Steinem, C. (2003) Biosensorische Anwendungen festkörperunterstützter Lipidmembranen auf planaren und porösen Oberflächen. 11. Heiligenstädter Kolloquium - Tagungsband, ISBN 3-00-011287-1.

Janshoff, A., Galla, H.-J., Steinem, C. (2003) Biochemical applications of solid supported membranes on gold surfaces: quartz crystal microbalance and impedance analysis. Planar lipid bilayers (BLMs) and their applications, ISBN 0-444-50940-2.


Steinem, C. (2002) Die Masse macht's - Der Schwingquarz in der Bioanalytik. Blick in die Wissenschaft 14, 12-17.

Hennesthal, C., Drexler, J., Steinem, C. (2002) Membrane-suspended nanocompartments based on ordered pores in alumina. ChemPhysChem 3, 885-889.

Kastl, K., Ross, M., Gerke, V., Steinem, C. (2002) Kinetics and thermodynamics of annexin A1 binding to solid-supported membranes: A QCM study. Biochemistry 41, 10087-10094.

Steinem, C. (2002) Die Zellmembran als Vorbild moderner Biosensoren. Biosystemtechnik: Innovative Biosystemtechnik - Sensorik, Aktorik und Auswertung biotechnologischer Prozesse, ISBN 3-00-009026-6.

Janshoff, A., Steinem, C. (2002) Biosensors, Porous Silicon. Encyclopedia of Smart Materials. M. Schwartz (ed.) John Wiley & Sons, Inc., 121-138.

Eing, A., Janshoff, A., Galla, H.-J., Block, C. Steinem, C. (2002) Quantification of the Raf-C1 interaction with solid-supported bilayers. ChemBioChem 3, 190-197.


Janshoff, A., Steinem, C. (2001) Scanning force microscopy of artificial membranes. ChemBioChem 2, 798-808.

Janshoff, A., Steinem, C. (2001) Energy landscapes of ligand-receptor couples probed by dynamic force spectroscopy. ChemPhysChem 2, 577-579.

Michalke, A., Galla, H.-J., Steinem, C. (2001) Channel activity of a phytotoxin of Clavibacter michiganense ssp. nebraskense in tethered membranes. Eur. Biophys. J. 30, 421-429.

Janshoff, A., Ross, M., Gerke, V., Steinem, C. (2001) Visualization of annexin I binding to calcium-induced phosphatidylserine domains. ChemBioChem 2, 587-590.

Janshoff, A., Steinem, C. (2001) Quartz crystal microbalance for bioanalytical applications. Sensors Update 9, 313-354.

Wegener, J., Janshoff, A., Steinem, C. (2001) The quartz crystal microbalance as a novel means to study cell-substrate interactions in situ. Cell Biochem. Biophys. 34, 121-151.

Michalke, A., Schürholz, T., Galla, H.-J., Steinem, C. (2001) Membrane activity of an anion channel from Clavibacter michiganense ssp. nebraskense. Langmuir 17, 2251-2257.

Ross, M., Steinem, C., Galla, H.-J., Janshoff, A. (2001) Visualization of chemical and physical properties of calcium-induced domains in DPPC/DPPS Langmuir-Blodgett layers. Langmuir 17, 2437-2445.


Hennesthal, C., Steinem, C. (2000) Pore-spanning lipid bilayers visualized by scanning force microscopy. J. Am. Chem. Soc. 122, 8085-8086.

Pignataro, B., Steinem, C., Galla, H.-J., Fuchs, H., and Janshoff, A. (2000) Specific adhesion of vesicles monitored by scanning force microscopy and quartz crystal microbalance. Biophys. J. 78, 487-498.

Galla, H.-J., Steinem, C., Janshoff, A. (2000) Die Quarzmikrowaage - Eine wiederentdeckte Technik erobert die moderne Bioanalytik. Bioforum 4, 210-213.

Janshoff, A., Steinem, C. (2000) Kraftmikroskopie an Biomembranen. Biospektrum 5, 401-406.

Janshoff, A., Galla, H.-J., Steinem, C. (2000) Mikrogravimetrische Sensoren in der Bioanalytik: Eine Alternative zu optischen Biosensoren? Piezoelectric mass sensing devices as biosensors - an alternative to optical biosensors? Angew. Chem. 112, 4164-4195; Angew. Chem. Int. Ed. 39, 4004-4032.

Janshoff, A., Steinem, C., Michalke, A., Henke, C., Galla, H.-J. (2000) Monofunctionalized beta-cyclodextrins as sensor elements for the detection of small molecules. Sens. Actuators B 70, 243-253.

Steinem, C., Galla, H.-J., Janshoff, A. (2000) Interaction of melittin with solid supported membranes. Phys. Chem. Chem. Phys. 2, 4580-4585.

Bong, D. T. Y., Janshoff, A., Steinem, C., Ghadiri, M. R. (2000) Membrane partitioning of the cleavage peptide in Flock House virus. Biophys. J. 78, 839-845.


Steinem, C., Vollmer, M. S., Janshoff, A., Ghadiri, M.R. (1999) Reversible photoisomerization of self-organized cylindrical peptide assemblies at air-water and solid interfaces. Langmuir 15, 3956-3964.

Vollmer, M. S., Clark, T. D.; Steinem, C., Ghadiri, M. R. (1999) Photoswitchable hydrogen-bonding in self-organized cylindrical peptide systems. Angew. Chem. Int. Ed. 38, 1598-1601.

Janshoff, A., Bong, D. T. Y., Steinem, C., Johnson, J. E., Ghadiri, M. R. (1999) An animal virus-derived peptide switches membrane morphology: Possible relevance to nodaviral transfection processes. Biochemistry 38, 5328-5336.

Bong, D. T. Y., Steinem, C., Janshoff, A., Johnson, J. E., Ghadiri, M. R. (1999) A highly membrane active peptide in Flock House virus: Implications for the mechanism of nodavirus infection. Chem. Biol. 6, 473-481.

Michalke, A., Janshoff, A., Steinem, C., Henke, C., Sieber, M., Galla, H.-J. (1999) Quantification of the host-guest interaction of charged guest molecules with chemisorbed cyclodextrin-derivatives. Anal. Chem. 71, 2528-2533.


Janshoff, A., Dancil, K.-P.S., Steinem, C., Greiner, D. P., Lin, V.S.-Y., Gurtner, C., Motesharei, K., Sailor, M. J.; Ghadiri, M. R.(1998) Macroporous p-type silicon Fabry-Perot layers. Fabrication, characterization, and applications in biosensing. J. Am. Chem. Soc. 120,12108-12116.

Steinem, C., Janshoff, A., Galla, H.-J. (1998) Evidence for multilayer formation of melittin on solid-supported phospholipid membranes by shear-wave resonator measurements. Chem. Phys. Lipids 95, 95-104.

Steinem, C., Janshoff, A., von dem Bruch, K., Reihs, K., Goossens, J., Galla, H.-J. (1998) Valinomycin-mediated transport of alkali cations through solid supported membranes. Bioelectrochem. Bioenerg. 45, 17-26.


Steinem, C., Janshoff, A., Wegener, J., Ulrich, W.-P., Willenbrink, W., Sieber, M., Galla, H.-J. (1997) Impedance and shear wave resonance analysis of ligand-receptor interaction at functionalized surfaces and of cell monolayers. Biosens. Bioelectronics 12, 787-808.

Steinem, C., Janshoff, A., Galla, H.-J., Sieber, M. (1997) Impedance analysis of the ion transport through gramicidin channels incorporated in solid supported lipid bilayers. Bioelectrochem. Bioenerg. 42, 213-220.

Steinem, C., Janshoff, A., Höhn, F., Sieber, M., Galla, H.-J. (1997) Proton translocation across bacteriorhodopsin containing solid supported lipid bilayers. Chem. Phys. Lipids 89, 141-152.

Galla, H.-J., Steinem, C., Reihs, K. (1997) Solid-supported membrane biosensors. Patent DE 19607279.

Janshoff, A., Steinem, C., Sieber, M., el Bâya, A., Schmidt, M. A., Galla, H.-J. (1997) Quartz crystal microbalance investigation of the interaction of bacterial toxins with ganglioside containing solid supported membranes. Eur. Biophys. J. 26, 261-270.


Janshoff, A., Steinem, C., Sieber, M., Galla, H.-J. (1996) Specific binding of peanut agglutinin to GM1-doped solid supported lipid bilayers investigated by shear wave resonator measurements. Eur. Biophys. J. 25, 105-113.

Steinem, C., Janshoff, A., Ulrich, W.-P., Sieber, M.; Galla, H.-J. (1996) Impedance analysis of supported lipid bilayer membranes: a scrutiny of different preparation techniques. Biochim. Biophys. Acta 1279, 169-180.

Henke, C., Steinem, C., Janshoff, A., Steffan, G., Luftmann, H., Sieber, M., Galla, H.-J. (1996) Self-assembled monolayers of monofunctionalized cyclodextrins onto gold: a mass spectrometric characterization and impedance analysis of host-guest interaction. Anal. Chem. 68, 3158-3165.

Janshoff, A., Wegener, J., Steinem, C., Sieber, M., Galla, H.-J. (1996) Applications of impedance spectroscopy in biochemistry and biophysics. Acta Biochim. Pol. 43, 339-348.