Göttingen Graduate School for Neurosciences, Biophysics, and Molecular Biosciences

Ehrenreich, Hannelore, Prof. Dr. Dr.


  • 1981 Doctor of Veterinary Medicine, University of Munich
  • 1983 Elective Period, University of Newcastle-upon-Tyne, England
  • 1985 Guest Lecturer, University of the Philippines, Manila
  • 1985 - 1986 Clinical Fellow, Department of Internal Medicine, University of Munich
  • 1987 Graduation (Medicine), University of Munich
  • 1987 - 1988 Residency, Department of Neurology, University of Munich
  • 1989 Doctor of Medicine, University of Munich
  • 1989 - 1991 Postdoctoral Fellow NIAID, NIH, Bethesda, MD, USA
  • 1992 - 1994 Residency, Departments of Neurology and Psychiatry, University of Göttingen
  • 1994 Habilitation (Neurology and Psychiatry)
  • 1994 - present Head, Clinical Neuroscience, Max Planck Institute of Experimental Medicine
  • 1995 - present Consultant & Professor of Neurology & Psychiatry, University of Göttingen
  • 2000 - 2002 Vice President, University of Göttingen
  • 2008 Professor of Biology and Psychology (Honorary), University of Göttingen
  • 2016 Member of the Leopoldina, German National Academy of Science



Major Research Interests

Translational Neuroscience

Research with particular focus on:

(1) Genetic and environmental underpinnings of neuropsychiatric diseases;

(2) Endogenous neuroprotection and neuroregeneration as therapeutic strategies for patients: Research centering on the brain erythropoietin system and hypoxia;

(3) Autoimmune and inflammatory processes contributing to neuropsychiatric phenotypes.



Homepage Department/Research Group

http://www.em.mpg.de/site/index.php?id=36



Selected Recent Publications


  • Mitjans M et al (2018) Violent aggression predicted by multiple pre-adult environmental hits. Mol Psychiatry.May 24. doi: 10.1038/s41380-018-0043-3. [Epub ahead of print]
  • Pan H et al (2018) Uncoupling the widespread occurrence of anti-NMDAR1 autoantibodies from neuropsychiatric disease in a novel autoimmune model. Mol Psychiatry. Feb 9. doi: 10.1038/s41380-017-0011-3. [Epub ahead of print]
  • Ehrenreich H et al (2018): OTTO: A new strategy to extract mental disease-relevant combinations of GWAS hits from individuals; Mol Psychiatry. Feb;23(2):476-486.
  • Janova H et al (2018) Microglia ablation alleviates myelin-associated catatonic signs in mice. J Clin Invest. 128(2):734-745.
  • Castillo-Gomez E et al (2016): All naturally occurring autoantibodies against the NMDA receptor subunit NR1 have pathogenic potential irrespective of epitope and immunoglobulin class. Mol Psychiatry, 22(12):1776-1784.
  • Hassouna I et al (2016): Revisiting adult neurogenesis and the role of erythropoietin for neuronal and oligodendroglial differentiation in the hippocampus. Mol Psychiatry, 21(12):1752-1767.
  • Stepniak B et al (2015): Accumulated common variants in the broader fragile X gene family modulate autistic phenotypes. EMBO Mol Med 7(12):1565-79
  • PGC (2014): Biological insights from 108 schizophrenia-associated genetic loci; Nature 511(7510):421-7.
  • Stepniak B et al (2014): Accumulated environmental risk determining age at schizophrenia onset, Lancet Psychiatry, 1(6):444-53. doi: 10.1016/S2215-0366(14)70379-7.
  • Hammer C et al (2014): Neuropsychiatric disease relevance of circulating anti-NMDA receptor autoantibodies depends on blood-brain barrier integrity. Mol Psychiatry. Oct;19(10):1143-9.