Ehrenreich, Hannelore, Prof. Dr. Dr.
- 1981 Doctor of Veterinary Medicine, University of Munich
- 1983 Elective Period, University of Newcastle-upon-Tyne, England
- 1985 Guest Lecturer, University of the Philippines, Manila
- 1985 - 1986 Clinical Fellow, Department of Internal Medicine, University of Munich
- 1987 Graduation (Medicine), University of Munich
- 1987 - 1988 Residency, Department of Neurology, University of Munich
- 1989 Doctor of Medicine, University of Munich
- 1989 - 1991 Postdoctoral Fellow NIAID, NIH, Bethesda, MD, USA
- 1992 - 1994 Residency, Departments of Neurology and Psychiatry, University of Göttingen
- 1994 Habilitation (Neurology and Psychiatry)
- 1994 - present Head, Clinical Neuroscience, Max Planck Institute of Experimental Medicine
- 1995 - present Consultant & Professor of Neurology & Psychiatry, University of Göttingen
- 2000 - 2002 Vice President, University of Göttingen
- 2008 Professor of Biology and Psychology (Honorary), University of Göttingen
- 2016 Member of the Leopoldina, German National Academy of Science
Major Research Interests
Research with particular focus on:
(1) Genetic and environmental underpinnings of neuropsychiatric diseases;
(2) Endogenous neuroprotection and neuroregeneration as therapeutic strategies for patients: Research centering on the brain erythropoietin system and hypoxia;
(3) Autoimmune and inflammatory processes contributing to neuropsychiatric phenotypes.
Homepage Department/Research Group
Selected Recent Publications
- Mitjans M et al (2018) Violent aggression predicted by multiple pre-adult environmental hits. Mol Psychiatry. May 24. doi: 10.1038/s41380-018-0043-3. [Epub ahead of print]
- Pan H et al (2018) Uncoupling the widespread occurrence of anti-NMDAR1 autoantibodies from neuropsychiatric disease in a novel autoimmune model. Mol Psychiatry. Feb 9. doi: 10.1038/s41380-017-0011-3. [Epub ahead of print]
- Ehrenreich H et al (2018): OTTO: A new strategy to extract mental disease-relevant combinations of GWAS hits from individuals; Mol Psychiatry.Feb;23(2):476-486.
- Janova H et al (2018) Microglia ablation alleviates myelin-associated catatonic signs in mice. J Clin Invest. 128(2):734-745.
- Castillo-Gomez E et al (2016): All naturally occurring autoantibodies against the NMDA receptor subunit NR1 have pathogenic potential irrespective of epitope and immunoglobulin class. Mol Psychiatry, 22(12):1776-1784.
- Hassouna I et al (2016): Revisiting adult neurogenesis and the role of erythropoietin for neuronal and oligodendroglial differentiation in the hippocampus. Mol Psychiatry, 21(12):1752-1767.
- Stepniak B et al (2015): Accumulated common variants in the broader fragile X gene family modulate autistic phenotypes. EMBO Mol Med 7(12):1565-79
- PGC (2014): Biological insights from 108 schizophrenia-associated genetic loci; Nature 511(7510):421-7.
- Stepniak B et al (2014): Accumulated environmental risk determining age at schizophrenia onset, Lancet Psychiatry, 1(6):444-53. doi: 10.1016/S2215-0366(14)70379-7.
- Hammer C et al (2014): Neuropsychiatric disease relevance of circulating anti-NMDA receptor autoantibodies depends on blood-brain barrier integrity. Mol Psychiatry. Oct;19(10):1143-9.