Göttingen Graduate School for Neurosciences, Biophysics, and Molecular Biosciences
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Steinem, Claudia, Prof. Dr.



  • 1987 - 1989 Studies of Biology at the University of Münster

  • 1989 - 1994 Studies of Chemistry at the University of Münster

  • 1994 - 1997 PhD thesis under supervision of Prof. Dr. H.-J. Galla

  • 1997 - 1998 Postdoctoral Researcher at the Scripps Research Institute (La Jolla, California, USA)

  • 1999 – 2001 Habilitation in Biochemistry at the University of Münster

  • 2001 – 2006 Associate professor (C3) for Bioanalytics and Biosensors at the University of Regensburg

  • 2006 Full professor (W3) for Biomolecular Chemistry at the University of Göttingen



Major Research Interests


Development and application of artificial lipid membranes on planar and porous supports, with particular emphasis on the function of ion channel proteins and transporters. Biophysical characterization of membrane-protein interactions.


Homepage Department/Research Group

http://www.uni-goettingen.de/de/213067.html



Selected Recent Publications


  • Song C, Weichbrodt C, Salnikovc ES, Dynowskid M, Forsberg BO, Bechinger B, Steinem C, de Groot BL, Zachariae U, Zeth K (2013) Crystal structure and functional mechanism of a human antimicrobial membrane channel. Proc Natl Acad Sci USA 110, 4586-4591


  • Orth, A., Johannes L, Römer W, Steinem C (2012) Creating and modulating microdomains in pore-spanning membranes. ChemPhysChem 13, 108-114


  • Lazzara TD, Carnarius C, Kokun M, Janshoff A, Steinem C (2011) Separating attoliter-sized compartments using fluid pore-spanning lipid bilayers. ACS Nano 5, 6935–6944


  • Bosk S, Braunger J, Gerke V, Steinem C (2011) Activation of F-actin binding capacity of ezrin: synergism of PIP2 interaction and phosphorylation. Biophys J 100, 1708-1717


  • Höfer I, Steinem C (2011) A membrane fusion assay based on pore-spanning membranes. Soft Matter 7, 1644-1647


  • Bernecker A, Wieneke R, Riedel R, Seibt M, Geyer A, Steinem C (2010) Tailored synthetic polyamines for controlled biomimetic silica formation. J Am Chem Soc 132, 1023-1031


  • Windschiegl B, Orth A, Römer W, Berland L, Stechmann B, Bassereau P, Johannes L, Steinem C (2009) Lipid reorganization induced by Shiga toxin clustering on planar membranes. PLoS ONE 4, e6238


  • Gaßmann O, Kreir M, Ambrosi C, Pranskevich J, Oshima A, Röling C, Sosinsky G, Fertig N, Steinem C (2009) The mutant of connexin26 reveals conductance states in pore-suspending membranes. J Struct Biol 168, 168-176







GGNB Steinem

Address
Prof. Dr. Claudia Steinem
Georg-August-Universität Göttingen
Institute for Organic and Biomolecular Chemistry
Tammannstr. 2
37077 Göttingen
Germany

phone: +49-(0)551-39 33294
fax: +49-(0)551-39 33228
email: csteine@gwdg.de

GGNB Affiliation
Biomolecules: Structure - Function -
Dynamics (GZMB)

Physics of Biological and Complex S
ystems (IMPRS)

Molecular Biology (IMPRS)