Göttingen Graduate School for Neurosciences, Biophysics, and Molecular Biosciences

Steinem, Claudia, Prof. Dr.

  • 1987 - 1989 Studies of Biology at the University of Münster
  • 1989 - 1994 Studies of Chemistry at the University of Münster
  • 1994 - 1997 PhD thesis under supervision of Prof. Dr. H.-J. Galla
  • 1997 - 1998 Postdoctoral Researcher at the Scripps Research Institute (La Jolla, California, USA)
  • 1999 – 2001 Habilitation in Biochemistry at the University of Münster
  • 2001 – 2006 Associate professor (C3) for Bioanalytics and Biosensors at the University of Regensburg
  • 2006 Full professor (W3) for Biomolecular Chemistry at the University of Göttingen

Major Research Interests

Development and application of artificial lipid membranes on planar and porous supports, with particular emphasis on the function of ion channel proteins and transporters. Biophysical characterization of membrane-protein interactions.

Homepage Department/Research Group


Selected Recent Publications

  • Schütte, O.M. Ries, A., Orth, A., Patalag, L.K., Römer, W., Steinem, C., Werz, D.B. (2014) Influence of Gb3 glycosphingolipids differing in their fatty acid chain on the phase behavior of solid supported membranes: Chemical syntheses and impact of Shiga toxin binding. Chem. Sci. 5, 3104-3114
  • Braunger, J. A., Brückner, B. R., Nehls, S., Pietuch, A., Gerke, V. Mey, I., Janshoff, A., Steinem, C. (2014) Phosphatidylinositol 4,5-bisphosphate alters the number of attachment sites between ezrin and actin filaments: a colloidal probe study. J. Biol. Chem. 289, 9833-9843
  • Song C, Weichbrodt C, Salnikovc ES, Dynowskid M, Forsberg BO, Bechinger B, Steinem C, de Groot BL, Zachariae U, Zeth K (2013) Crystal structure and functional mechanism of a human antimicrobial membrane channel. Proc Natl Acad Sci USA 110, 4586-4591

  • Orth, A., Johannes L, Römer W, Steinem C (2012) Creating and modulating microdomains in pore-spanning membranes. ChemPhysChem 13, 108-114

  • Lazzara TD, Carnarius C, Kokun M, Janshoff A, Steinem C (2011) Separating attoliter-sized compartments using fluid pore-spanning lipid bilayers. ACS Nano 5, 6935–6944

  • Bosk S, Braunger J, Gerke V, Steinem C (2011) Activation of F-actin binding capacity of ezrin: synergism of PIP2 interaction and phosphorylation. Biophys J 100, 1708-1717

  • Höfer I, Steinem C (2011) A membrane fusion assay based on pore-spanning membranes. Soft Matter 7, 1644-1647

  • Bernecker A, Wieneke R, Riedel R, Seibt M, Geyer A, Steinem C (2010) Tailored synthetic polyamines for controlled biomimetic silica formation. J Am Chem Soc 132, 1023-1031

  • Windschiegl B, Orth A, Römer W, Berland L, Stechmann B, Bassereau P, Johannes L, Steinem C (2009) Lipid reorganization induced by Shiga toxin clustering on planar membranes. PLoS ONE 4, e6238

  • Gaßmann O, Kreir M, Ambrosi C, Pranskevich J, Oshima A, Röling C, Sosinsky G, Fertig N, Steinem C (2009) The mutant of connexin26 reveals conductance states in pore-suspending membranes. J Struct Biol 168, 168-176