Göttinger Graduiertenschule für Neurowissenschaften, Biophysik und Molekulare Biowissenschaften

Steinem, Claudia, Prof. Dr.


  • 1987 - 1994 Studies in Biology and Chemistry and Diploma in Chemistry, University of Münster, Prof. Dr. H.-J. Galla
  • 1994 - 1997 Doctior in Chemistry, University of Münster, Prof. Dr. H.-J. Galla
  • 1997 Postdoctoral Researcher, Institute of Biochemistry, University of Münster
  • 1997 - 1998 Postdoctoral Fellow, Scripps Research Institute, La Jolla, California, USA
  • 1999 - 2001 Habilitation in Biochemistry, Institute of Biochemistry, University of Münster, Prof. Dr. H.-J. Galla
  • 2001 – 2006 Associate professor for Bioanalytics and Biosensors, University of Regensburg
  • 2006 Full professor for Biomolecular Chemistry, University of Göttingen
  • Since 2017 MPG fellow of the Max-Planck Institute for Dynamics and Self-Organization, Göttingen



Major Research Interests


New artificial membrane systems based on highly ordered porous substrates; Functional insertion of ion channels and protein pumps; Development and application of fusion assays; Quantification and visualization of protein-membrane and protein-cytoskeleton interactions; Hierarchical silica formation in vitro


Homepage Department/Research Group

http://www.uni-goettingen.de/de/213067.html



Selected Recent Publications


  • Schütte OM, Mey I, Enderlein J, Savic F, Geil B, Janshoff A, Steinem C (2017) Size and mobility of lipid domains tuned by geometrical constraints. Proceedings of the National Academy of Sciences 114(30) DOI:10.1073/pnas.1704199114.
  • Gleisner M, Kroppen B, Fricke C, Teske N, Kliesch TT, Janshoff A, Meinecke M, Steinem C (2016) Epsin N-terminal Homology Domain (ENTH) Activity as a Function of Membrane Tension. Journal of Biological Chemistry 291(38) DOI:10.1074/jbc.m116.731612.
  • Ludolphs M, Schneeberger D, Soykan T, Schäfer J, Papadopoulos T, Brose N, Schindelin H, Steinem C (2015) Specificity of Collybistin-Phosphoinositide Interactions. Journal of Biological Chemistry 291(1) DOI:10.1074/jbc.m115.673400.
  • Rost U, Steinem* C, Diederichsen* U (2016) β-Glutamine-mediated self-association of transmembrane β-peptides within lipid bilayers. Chemical Science 7(9) DOI:10.1039/c6sc01147k.
  • Schütte OM, Ries A, Orth A, Patalag LJ, Römer W, Steinem* C, Werz* DB (2014) Influence of Gb3 glycosphingolipids differing in their fatty acid chain on the phase behaviour of solid supported membranes: chemical syntheses and impact of Shiga toxin binding. Chemical Science 5(8) DOI:10.1039/c4sc01290a.
  • Braunger JA, Brückner BR, Nehls S, Pietuch A, Gerke V, Mey I, Janshoff A, Steinem C (2014) Phosphatidylinositol 4, 5-Bisphosphate Alters the Number of Attachment Sites between Ezrin and Actin Filaments. Journal of Biological Chemistry 289(14) DOI:10.1074/jbc.m113.530659.
  • Song C, Weichbrodt C, Salnikov ES, Dynowski M, Forsberg BO, Bechinger B, Steinem C, de Groot BL, Zachariae U, Zeth K (2013) Crystal structure and functional mechanism of a human antimicrobial membrane channel. Proceedings of the National Academy of Sciences 110(12) DOI:10.1073/pnas.1214739110.
  • Lazzara TD, Carnarius C, Kocun M, Janshoff A, Steinem C (2011) Separating Attoliter-Sized Compartments Using Fluid Pore-Spanning Lipid Bilayers. ACS Nano 5(9) DOI:10.1021/nn201266e.
  • Bernecker A, Wieneke R, Riedel R, Seibt M, Geyer A, Steinem C (2010) Tailored Synthetic Polyamines for Controlled Biomimetic Silica Formation. Journal of the American Chemical Society 132(3) DOI:10.1021/ja9061163.
  • RömerW, Berland L, Chambon V, Gaus K, Windschiegl B, Tenza D, Aly MRE, Fraisier V, Florent JC, Perrais D, Lamaze C, Raposo G, Steinem C, Sens P, Bassereau P, Johannes L (2007) Shiga toxin induces tubular membrane invaginations for its uptake into cells. Nature 450(7170) DOI:10.1038/nature05996.