Event
Thermodynamics of error correction| Title of the event | Thermodynamics of error correction |
| Series | LMP Seminar (video conference) |
| Organizer | Physik lebender Materie |
| Speaker | Prof. Dr. Simone Pigolotti |
| Speaker institution | Okinawa Institute of Science and Technology Graduate University (OIST), Japan |
| Type of event | Seminar |
| Category | Forschung |
| Registration required | Nein |
| Details | Biological systems are able to replicate information with outstanding accuracy. In biochemical pathways such as those leading to DNA duplication or protein translations, different monomers can be distinguished because of equilibrium free-energy differences or via non-equilibrium mechanisms. I will show how, in simple copying reactions, these two discrimination modes are mutually exclusive and lead to opposite tradeoffs between error, dissipation and reaction velocity. In multi-step reactions, such as in kinetic proofreading, these different modes can be combined to improve overall accuracy. In the second part of my talk, I will present recent results about fluctuations in accuracy and speed of these reactions. |
| Date | Start: 12.01.2021, 14:00 Uhr Ende: 12.01.2021 , 15:30 Uhr |
| Location |
Max-Planck-Institut für Dynamik und Selbstorganisation (MPIDS) (Am Faßberg 17) Video conference at www.zoom.us Meeting ID: 997 1155 2453 Passcode: 771001 |
| Contact |
Prof. Dr. Ramin Golestanian golestanian-office@ds.mpg.de |