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Veranstaltung

Physics of cell motility - shape, polarity, and the cytoskeleton

Titel der Veranstaltung Physics of cell motility - shape, polarity, and the cytoskeleton
Reihe LMP Seminar (video conference)
Veranstalter Physik lebender Materie
Referent/in Prof. Dr. Brian Camley
Einrichtung Referent/in Johns Hopkins University, USA
Veranstaltungsart Seminar
Kategorie Forschung
Anmeldung erforderlich Nein
Beschreibung Crawling eukaryotic cells are soft matter driven out of equilibrium by active forces - a great playground for physicists - but their physics also strongly constrains cell function. I will present two stories from recent work from my group, one on cell polarity, and one on cytoskeletal dynamics and active gels. First, I will discuss the group's recent work on how reactions on the cell's surface can become sensitive to cell shape. This shape sensing can lead to surprising new behaviors, like single cells developing a spontaneous circular motion, but can be disrupted by membrane roughness. Secondly, I will discuss the physics of extreme events in cytoskeletal dynamics. Recent experimental work suggests that tracers attached to the cell's cortex undergo diffusion with rare large jumps - diffusion with heavy tails. I will show how heavy tails arise naturally from a classical theory of actively-driven gels, and how this depends on the mechanics and geometry of the cortex.
Zeit Beginn: 06.04.2021, 14:00 Uhr
Ende: 06.04.2021 , 15:30 Uhr
Ort Max-Planck-Institut für Dynamik und Selbstorganisation (MPIDS) (Am Faßberg 17)
Video conference at www.zoom.us Meeting ID: 997 1155 2453 Passcode: 771001
Kontakt Dr. Evelyn Tang
evelyn.tang@ds.mpg.de