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Event

Localization in Biological Networks

Title of the event Localization in Biological Networks
Series MPIDS Colloquium
Organizer Living Matter Physics
Speaker Prof. Dr. David Nelson
Speaker institution Lyman Laboratory of Physics, Harvard University, Cambridge, MA, USA
Type of event Seminar
Category Forschung
Registration required Nein
Details We describe the spectra and localization properties of the N-site banded one-dimensional highly asymmetric random matrices that arise naturally in sparse neural networks, and also in deep learning models with tunable feed-forward interaction strengths. When N is large, approximately equal num-bers of random excitatory and inhibitory connections lead to spatially localized eigenfunctions, and an intricate eigenvalue spectrum in the complex plane that controls the spontaneous activity and induced response. A finite fraction of the eigenvalues condense onto the real or imaginary axes, with remark-able spectral symmetries and a strongly diverging in the localization length near the origin. When chains with periodic boundary conditions become directed, with a systematic directional bias superim-posed on the randomness, a hole centered on the origin opens up in the density-of-states in the com-plex plane. All states are extended on the rim of this hole, while the localized eigenvalues outside the hole are unchanged. Similar results are obtained for more realistic neural networks that obey "Dale's Law" (each site is purely excitatory or inhibitory). Related problems arise in random ecological net-works and in chains of artificial cells with randomly coupled gene expression patterns.
Date Start: 03.02.2021, 14:15 Uhr
Ende: 03.02.2021 , 15:15 Uhr
Location Max-Planck-Institut für Dynamik und Selbstorganisation (MPIDS) (Am Faßberg 17)
Video conference at www.zoom.us Meeting ID: 959 2774 3389 Passcode: 651129
Contact 0551/5176-155
evelyn.tang@ds.mpg.de
File attachment 210203_colloquium_nelson.pdf