Andrasch Jörgensen

EDUCATION

College / University

Philipps-University Marburg

Highest Degree

Bachelor of Science

Major Subjects

Biomedical Science (Human Biology), Major Tumor Biology

Country

Germany

Lab Experience

Cell Culture: Eukaryotic cell culture with cell lines and with primary immune cells
Immunology: Purification of murine splenic immune cells by MACS, CTL differentiation, flow cytometry, FACS, in vitro 2D cytotoxicity assay, 3D multicellular tumor spheroids co-cultures, ELISA
Molecular Biology: Protein extraction, SDS-PAGE, Immunoblotting, Basics of Protein purification, RNA extraction, cDNA synthesis, RT-qPCR, cloning, transfection, lentiviral transduction Confocal-Light-Microscopy
Computational: Primer Design, GraphPad Prism, Imaris, Image J, FlowJo

Projects / Research

2025: Implication of Protein Arginine Methyltransferase 1 in the Activation and Effector Function of Cytotoxic Immune Cells in Context of the Pancreatic Ductal Adenocarcinoma
2024: Lentiviral transduction of SCLC cells to induce CRISPR/Cas9-mediated knockout

Scholarships / Awards

2025 – 2026:	Stipend by the International Max Planck Research School
2023 – 2026:	Scholarship of the Friedrich-Ebert-Society

SCIENTIFIC INTERESTS AND GOALS

Proteins and their interactions with themselves and nucleic acids affect all aspects of life. Their dysregulation conduces to diseases of various kinds, especially cancer. Despite our progress in understanding, we often lack detailed knowledge about major pathological pathways, leading to the necessity of conducting more research. While I am currently interested in tumor progression through immune evasion and therapy resistance, I am eager to broaden my horizon. I am not just interested in viewing molecular interactions isolated but also in keeping an eye on alterations to the overall cellular characteristics and how interactions with other cells can drive molecular reprogramming. In Göttingen, I hope to expand my current knowledge and skill set and explore new scientific areas out of my comfort zone to create a large scientific toolbox.