Scherberger, Hansjörg, Prof. Dr.

Group Leader Primate Neurobiology

  • Dipl. math. (MS Math), University of Freiburg, Germany, 1993
  • Dr. med. (MD), University of Freiburg, Germany, 1996
  • Postdoctoral Fellow, Dept of Neurology, University of Zürich, Switzerland, 1995 – 1998
  • Postdoctoral Fellow, California Institute of Technology, 1998 – 2000
  • Senior Postdoctoral Fellow, California Institute of Technology, 2000 – 2004
  • Work group leader, Institute of Neuroinformatics, ETH / University of Zürich, Switzerland, 2004 – 2009
  • Professor for Primate Neurobiology, University of Göttingen and Deutsches Primatenzentrum GmbH, since 2008

Major Research Interests

We are interested in how hand movements are generated in the primate brain and how intentions to grasp objects can be decoded for controlling a neural prosthesis. For this, we investigate the cortical representation of hand movements in motor-related cortical areas and their relation to sensory systems and decision making. Furthermore, we are developing brain-machine interfaces that can read out such movement intentions to control robotic devices. Such systems could be useful for future applications aiming to restore hand function in paralyzed patients.

Homepage Department/Research Group

Selected Recent Publications

  • Greulich RS, Adam R, Everling S, Scherberger H (2020): Shared functional connectivity between the dorso medial and dorso ventral streams in macaques. Scientific Reports10:18610.
  • Michaels JA, Schaffelhofer S, Agudelo-Toro A, Scherberger H (2020): A goal-driven modular neural network predicts parietofrontal neural dynamics during grasping. Proc Nat. Acad. Science USA 117(50):32124-32135.
  • Michaels JA, Dann B, Intveld RW, Scherberger H (2018). Neural dynamics of variable grasp movement preparation in the macaque fronto-parietal network. J Neuroscience 38:5759–5773.
  • Scherberger H (2017) Stirred, Not Shaken: Motor Control with Partially Mixed Selectivity. Neuron 95(3):479-481.
  • Michaels JA, Dann B, Scherberger H (2016) Neural Population Dynamics during Reaching Are Better Explained by a Dynamical System than Representational Tuning. PLoS Computational Biology 12(11):e1005175.
  • Dann B, Michaels JA, Schaffelhofer S, Scherberger H (2016) Uniting functional network topology and oscillations in the fronto-parietal single unit network of behaving primates. eLife 5:e15719.
  • Schaffelhofer S, Scherberger H (2016) Object vision to hand action in macaque parietal, premotor, and motor cortices. eLife 5:e15278.
  • Janssen P, Scherberger H (2015) Visual Guidance in Control of Grasping. Annual Review of Neuroscience 38:69–86.
  • Schaffelhofer S, Agudelo-Toro A, Scherberger H (2015) Decoding a Wide Range of Hand Configurations from Macaque Motor, Premotor, and Parietal Cortices. J Neuroscience 35:1068–1081.
  • Schaffelhofer S, Scherberger H (2012) A new method of accurate hand- and armtracking for small Primates. Journal of Neural Engineering 9:026025.