The role of carbonic anhydrases in the development of Sordaria macrospora

Carbonic anhydrases (CAs) are metalloenzymes that catalyze the interconversion of carbon dioxide and bicarbonate with high efficiency. This reaction is fundamental to biological processes such as respiration, photosynthesis, pH homeostasis, CO2 transport and electrolyte secretion. Recent work demonstrates that CAs play an important role in the CO2-sensing system of fungal pathogens and in the regulation of sexual development. We focus on CA functions of the four CA genes in S. macrospora.