Toma Yakulov


College / University

Sofia University "St. Kl. Ohridski"

Highest Degree

Master of Science

Major Subjects

Biochemistry, Molecular Biology




Lab Experience

DNA extraction and purificartion; PCR based methods; SSCP; RFLP; direct sequencing

Projects / Research

  • 2002: "Met129Val Prion Protein Polymorphism Genotyping in Bulgarian and Roma Population"
  • 2003: "Associative study of polymorphic markers in estrogen receptor (ER) and vitamin D receptor (VDR) genes in patients with colorectal cancer"

Poster presentation

Yakulov T., Savov A., Laplanche J.L., Kremensky I. "Met129Val Prion Protein Polymorphism Genotyping in Bulgarian and Roma Population", 2002, 5th Balkan Congress on Human Genetics, Sofia, Bulgaria

Scholarships / Awards

2003 – 2004: Stipend International Max Planck Research School
1998 – 2003: Scholarship for academic excellence, Sofia University "St. Kl. Ohridski", Sofia, Bulgaria


In his nobel lecture in 1977 Prof. Ilya Prigogine wrote that non-equilibrium may be a source of order. Irreversible processes may lead to a new type of dynamic states of matter which he called "dissipative structures". These structures manifest a coherent, supermolecular character which leads to new, quite spectacular manifestations. Such structures in biology are my special area of interest.