Shruti Thottakara Guruvayurappan

EDUCATION

College / University

Shiv Nadar University, Delhi-NCR

Highest Degree

Bachelor of Science

Major Subjects

Molecular Biology, Biochemistry, Immunology, Cell Biology, Microbiology, Bioinformatics, Genetics

Country

India

Lab Experience

Agarose gel electrophoresis & SDS-PAGE, Polymerase Chain Reaction (PCR), Molecular Cloning, Zebrafish Care and Handling
Softwares: Chimera, Amber, Visual Molecular Dynamics (VMD), Biorender, SnapGene

Projects / Research

07/2022 – 05/2023: Final Year Undergraduate Thesis Project under the Department of Life Sciences, SNU: Adapting a degron-based, inducible protein degradation system in zebrafish through transposon-mediated transgenesis
05/2021 – 07/2022: Opportunities for Undergraduate Research (OUR) program under the Department of Chemistry, SNU: Investigating the key interactions between a DNA lesion and the human DNA repair enzyme, O6-alkylguanine-DNA alkyltransferase (hAGT) and elucidating the mechanism of demethylation of the guanine base via Molecular Dynamic Simulations. (Publication: Front. Mol. Biosci., 14 September 2022, Sec. Biological Modeling and Simulation)

Scholarships / Awards

2023 – 2024:	Stipend by the International Max Planck Research School
2019 – 2023:	Academic Merit Scholarship at Shiv Nadar University with 100% Tuition fee Waiver
2019 – 2022:	Dean’s List Awardee, Shiv Nadar University - Excellent Academic Performance for 5 consecutive Semesters

SCIENTIFIC INTERESTS AND GOALS

I believe that the embryo is a treasure trove of information on how life develops from a single cell to a fully developed, multicellular creature. Another aspect of biology that I am interested in is the Immune system and its ability to mount defense and offense against a myriad of threats to the human body. It amazes me to no end on how the interplay of molecular, cellular or genetic mechanisms inside a single cell makes complex life possible. Hence, I would like to work towards contributing to fundamental knowledge to gain insights into the underpinnings of development and regeneration. This insight can further pave way in understanding the various disorders associated with the dysregulation of these developmental processes. In the future, I would like to do research towards enabling therapeutic interventions as well.