Stahl-Hennig, Christiane, Dr. med. vet.
Head of Unit of Infection Models at the German Primate Center, Göttingen
- 2008 - today: Creating an independent working group and then becoming head of the unit "Infection Models" at the German Primate Center
- 1988 - 2007: Head of the working group "Animal models" in the Department of Virology and Immunology, German Primate Center (Head of Department: Prof. G. Hunsmann)
- August 1992: Award of the specialist veterinarian for Virology
- 1984 - 1987: Researcher at the Institute of Virology at the University of Veterinary Medicine in Hannover, Germany
- 1983 - 1984: Assistant veterinarian in a mixed veterinary practice in Rendsburg, Schleswig-Holstein
- December 1983: Doctorate Dr. med. vet.
- 1982 - 1983: Doctoral thesis at the Clinic for Cattle Diseases at the University of Veterinary Medicine in Hannover, Germany
Major Research Interests
A key aspect of Dr. Christiane Stahl-Hennig’s research includes studies on preclinical prophylactic vaccines against various human pathogenic viral agents, primarily against human immunodeficiency virus (HIV) but also against orthopox viruses and respiratory syncytial virus. The ultimate goal is the development of needle free vaccination techniques. In addition, studies on the pathogenesis and pre-exposure prophylaxis are conducted with the help of the AIDS macaque model. In this context, the unit focuses on the research of various mucosal compartments.
Homepage Department/Research Group
Selected Recent Publications
- Mätz-Rensing, K.; Stahl-Hennig, C.; Kramski, M.; Pauli, G.; Ellerbrok, H.; Kaup, F-J (2012) The pathology of experimental poxvirus infection in common marmosets (Callithrix jacchus): further characterization of a new primate model for orthopoxvirus infections3. J Comp Pathol. 146(2-3):230-42.
- Nieto, K.; Stahl-Hennig, C.; Leuchs, B.; Müller, M.; Gissmann, L.; Kleinschmidt, J. (2012) Intranasal Vaccination with AAV5 and 9 Vectors against Human Papillomavirus Type 16 in Rhesus Macaques. Hum Gene Ther. 23
- Tenbusch, M.; Ignatius, R.; Temchura, V.; Nabi, G.; Tippler, B.; Stewart-Jones, G.; Salazar; A.M.; Sauermann, U.; Stahl-Hennig, C.; Überla, K. (2012) Risk of immunodeficiency virus infection may increase with vaccine-induced immune response. J Virol 86 (19). 10533-9
- Tenbusch, M.; Ignatius, R.; Nchinda, G.; Trumpfheller, C.; Salazar, A. M.; Töpfer, K.; Sauermann, U.; Wagner, R.; Hannaman, D.; Tenner-Racz, K.; Racz, P.; Stahl-Hennig, C.; Uberla, K. (2012) Immunogenicity of DNA vaccines encoding simian immunodeficiency virus antigen targeted to dendritic cells in rhesus macaques. PLos ONE 7 (6), e39038
- Schultheiß, T.; Schulte, R.; Sauermann, U.; Ibing, W.; Stahl-Hennig, C. (2011) Strong mucosal immune responses in SIV infected macaques contribute to viral control and preserved CD4+ T-cell levels in blood and mucosal tissues. Retrovirology. 8:24.
- Schultheiss T, Stahl-Hennig C. (2011) Correlation between CD4+ T-cell loss and Gag-specific T cells in different intestinal sites of chronically SIV-infected rhesus monkeys. AIDS. 2011 Feb 20;25(4):429-33.
- Stahl-Hennig C, Eisenblätter M, Jasny E, Rzehak T, Tenner-Racz K, Trumpfheller C, Salazar AM, Uberla K, Nieto K, Kleinschmidt J, Schulte R, Gissmann L, Müller M, Sacher A, Racz P, Steinman RM, Uguccioni M, Ignatius R. (2009). Synthetic double-stranded RNAs are adjuvants for the induction of T helper 1 and humoral immune responses to human papillomavirus in rhesus macaques. PLoS Pathog (PLoS pathogens)