Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und Molekulare Biowissenschaften

Ebert, Antje, PD Dr.

Research group leader at the Department of Cardiology and Pneumology


  • 2000 - 2006 Diploma in Biology, studies at the Universities of Mainz and Heidelberg, Cardiff University of Wales/UK, Johns Hopkins University MD/USA
  • 2006 - 2010 PhD at Heidelberg University, Biochemistry Center (Graduate Research College 1188)
  • 2010 - 2015 Postdoctoral fellow at Stanford University School of Medicine, Cardiovascular Institute (DFG fellowship); Department of Chemical and Systems Biology (Associated member)
  • 2015 - 2016 Instructor at Stanford University School of Medicine, Cardiovascular Institute; Department of Chemical and Systems Biology (Associated member)
  • since 2016 Research group leader at the University Medical Center Göttingen, Department of Cardiology and Pneumology
  • 2021 Habilitation in Molecular Biology and Biochemistry



Major Research Interests
Molecular interactions and signaling in cardiomyopathy
Our group studies the cell biology of cardiovascular diseases. We utilize human model systems such as induced pluripotent stem cells (iPSCs) in combination with site-specific genome editing, as well as biochemical, biophysical, and systems medicine approaches. With these interdisciplinary tools, we investigate the molecular functions of cardiac diseases, such as dilated and hypertrophic cardiomyopathy (DCM/HCM) as well as cardiac ischemia, leading causes of heart failure world-wide. We are focusing on molecular and biophysical signaling circuits that regulate intracellular transport processes, organelle function, and homeostasis in cardiomyocytes, endothelial cells, and other cells of the cardiac vasculature as well as their interfaces with the immune and neuronal systems. Our goals are to characterize and rescue molecular patho-phenotypes in human 2D/3D models of iPSC-derived cells, in live primary cell types of the heart as well as in cardiac tissues derived from adult patients. Ultimately, we aim to contribute novel therapeutic and regenerative directions for cardiac disease.


Homepage Department/Research Group
https://herzzentrum.umg.eu/cardiovascular-cell-biology-and-systems-medicine//index.html
http://www.ebert-lab.com/groupmembers.html

ORCID: 0000-0002-3642-242X