Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und Molekulare Biowissenschaften

Urlaub, Henning, Prof. Dr.

Group Leader - Bioanalytical Mass Spectrometry Group

  • from 2010: Group leader “Bioanalytical Mass Spectrometry” group at the Max Planck Institute for Biophysical Chemistry, Göttingen and “Bioanalytics” group at University Medical Center Göttingen (UMG) within Dept. of Clinical Chemistry
  • 2010: Professor at the Faculty of Medicine at Georg August University Göttingen
  • 2005: Research group “Bioanalytical Mass Spectrometry Group” at the Max Planck Institute for Biophysical Chemistry
  • 2001: Responsibility for running the mass spectrometry unit in the Dept. of Cellular Biochemistry at the Max Planck Institute for Biophysical Chemistry in Göttingen
  • 2000-2001: Guest researcher at the EMBL in Heidelberg, Germany, in the group of Dr. Matthias Wilm
  • 1997-2001: Post-Doc at the "Institut für Molekularbiologie und Tumorforschung" (IMT) of the Philipps University of Marburg, Germany (Group of Reinhard Lührmann) and at the Max Planck Institute for Biophysical Chemistry in Göttingen (Group of Reinhard Lührmann)
  • 1993-1996: Ph.D. and Post-Doc in the research group of Prof. Brigitte Wittmann-Liebold at the Max Delbrück Center for Molecular Medicine (MDC) in Berlin
  • 1992-1993: Diploma thesis in the research group of Prof. Volker A. Erdmann at the Institute of Biochemistry of the Free University of Berlin
  • 1987-1993: Studied biochemistry at the Free University of Berlin, Germany

    • Major Research Interests
    Modern mass-spectrometric methods have become key technologies in the life sciences. We apply “state-of-the-art” mass spectrometry to elucidate quantitative changes of proteins and their post-translational modifications derived from different samples, including tissue, cells, organelles, and cell compartments. In addition, we apply mass spectrometric (MS) methods to monitor dynamic changes of protein and protein-ligand complexes through use of cross-linking. Following main projects are investigated by the use of MS are: 1. Monitoring protein abundance, modifications and interactions in the non-stimulated and stimulated synapse by MS, 2. Protein-protein cross-linking combined with MS in stimulated and resting B cells, 3. Method development in protein-protein, protein-RNA and protein-DNA cross-linking combined with MS.

    Homepage Department/Research Group
    https://www.mpinat.mpg.de/urlaub

    ORCID: 0000-0003-1837-5233