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Event

Physics of cell motility - shape, polarity, and the cytoskeleton

Title of the event Physics of cell motility - shape, polarity, and the cytoskeleton
Series LMP Seminar (video conference)
Organizer Physik lebender Materie
Speaker Prof. Dr. Brian Camley
Speaker institution Johns Hopkins University, USA
Type of event Seminar
Category Forschung
Registration required Nein
Details Crawling eukaryotic cells are soft matter driven out of equilibrium by active forces - a great playground for physicists - but their physics also strongly constrains cell function. I will present two stories from recent work from my group, one on cell polarity, and one on cytoskeletal dynamics and active gels. First, I will discuss the group's recent work on how reactions on the cell's surface can become sensitive to cell shape. This shape sensing can lead to surprising new behaviors, like single cells developing a spontaneous circular motion, but can be disrupted by membrane roughness. Secondly, I will discuss the physics of extreme events in cytoskeletal dynamics. Recent experimental work suggests that tracers attached to the cell's cortex undergo diffusion with rare large jumps - diffusion with heavy tails. I will show how heavy tails arise naturally from a classical theory of actively-driven gels, and how this depends on the mechanics and geometry of the cortex.
Date Start: 06.04.2021, 14:00 Uhr
Ende: 06.04.2021 , 15:30 Uhr
Location Max-Planck-Institut für Dynamik und Selbstorganisation (MPIDS) (Am Faßberg 17)
Video conference at www.zoom.us Meeting ID: 997 1155 2453 Passcode: 771001
Contact Dr. Evelyn Tang
evelyn.tang@ds.mpg.de