What we do

As part of both the IOBC and the MBEx Cluster of Excellence , our research lies at the interphase of synthetic organic chemistry, photochemistry, photophysics, biochemistry, and biology. Consequently, all projects have a highly interdisciplinary character and often involve collaborations with research groups of neighboring disciplines.

(1) Organic Synthesis of Photoactive Compounds and Amino Acids
Overview of synthetic and analytical techniques
• Organic synthesis of dyes using a mixture of traditional and modern techniques
• Microwave-assisted automated solid phase peptide synthesis
• Synthesis both under irradiation and in the absence of light
• Handling of both hydrophobic and hydrophilic organic compounds
• Isolation & purification techniques, such as normal-phase and reversed-phase chromatography, crystallization, or (semi-)preparative HPLC

(2) Compound Characterization
methods for characterization
• Handling of light-sensitive compounds
• Analysis by NMR, HPLC, HPLC-MS, UV-Vis and fluorescence spectroscopy

(3) Photophysical & Photochemical Characterizationn
Pictures of photochemical experiments
• Kinetic analysis and quantification of photochemical transformations
• In operando UV-Vis spectroscopy

(4) Irradiation Experiments in Biomimetic, Biohybrid, and Biological Systems and Models
Irradiation Experiments
• light-mediated activation and deactivation of bioactive compounds
• light-mediated structural change of bio(hybrid)molecules
• development of multi-responsive and l-orthogonal systems for probes in chemical biology

What do we expect?

Undergraduate Students
• interest in organic synthesis of colored compounds and/or interest in spectroscopic techniques and/or chemical biology,
• curiosity in learning new techniques and working in more than one classical discipline

Graduate Students
• have a solid background in organic synthesis,
• have some experience in data processing and analysis,
• ideally have some experience in optical spectroscopy and/or organic photochemistry and/or biochemistry
• be creative, and curious in acquiring new techniques

Senior Researchers
• have a solid background in organic synthesis,
• have experience and designing and conducting a research project (appropriate to the stage)
• have experience in guiding and supervising junior group members,
• have experience in data processing and analysis,
• ideally have some experience in optical spectroscopy and/or organic photochemistry and/or biochemistry
• are creative, and curious in acquiring new techniques

Join us!

Undergraduate Students:
We offer research topics for interns at the Bachelor’s and Master’s level as well as for Bachelor’s and Master’s projects. We host both students from the University of Göttingen as well as exchange students or guests for research stays of flexible length.

Graduate Students/Postdoctoral Researchers:
Open positions for PhD students and postdocs will advertised here. Candidates who are interested in applying for own funding by acquiring an independent research fellowship (German Scholarship Foundations, FCI; industry sponsored fellowship, Marie-Curie, Humboldt, DFG, DAAD, etc. ) to join one of our research programs can expect extensive support for their preparation. Please contact NAS in advance to discuss potential projects.


If you are interested in one of the above mentioned options, please contact nadja.simeth@uni-goettingen.de directly with your CV, transcript or records, and name and email address of at least one reference (external applications) and area of interest or visit us in our lab!
Undergraduate students are cordially invited to approach NAS or our graduate students informally by simply dropping by our labs and offices and introduce themselves.