"Structural biochemistry" (12 C, 14 WLH) [M.Bio.106]

Learning outcome, core skills Methods in Structural Biochemistry, structure and function of biological macromolecules. Structure and folding of proteins, structure-function relationships, protein-protein and protein-nucleic acid complexes. Structure-based drug-design, molecular recognition. Handling of state of the art equipment, critical dealing with current biochemical topics, detailed analysis of experiments and their presentation. Independent acquisition of professional knowledge from publications by active participation in the seminar.

Examination requirements: knowledge of the basics in structural biochemistry, especially: * biochemical and analytic methods used in the characterization of proteins and macromolecular complexes * characteristics of selected proteins and protein complexes * the basics of structural resolution and the structural characteristics of proteins and nucleic acids

1. Lecture:»Structural biochemistry« (3 WLH),
2. Seminar: »Structural biochemistry« (1 WLH),
3. Methods course: »Structural biology« (10 WLH)

Examination: Written examination (90min, 80% of grade), oral presentation within seminar (15min, 10% of grade) and protocol (max 20 pages, 10% of grade)
Prerequisite for examination: regular participation in practical course and protocol

Selection options

Admission requirements
can't be combined with key competence modules M.Bio.156 and M.Bio.166

Recommended previous knowledge

Number of repeat examinations permitted

Course frequency
each summer-semester

1 semester


Maximum number of students

360 h (196/164 h, Attendance time /Self-study time)

Person responsible for module
Prof. Dr. Ralf Ficner