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A02 - Geometry of bio-polymer conformational dynamics

PIs: Prof. Dr. Jörg Enderlein; Prof. Dr. Anja Sturm; Prof. Dr. Max Wardetzky

This project aims at combining state-of-the-art coarse-grained models for the stochastic dynamics of thin elastic rods with single-molecule fluorescence-spectroscopic experiments that allow for directly measuring conformational fluctuations of intrinsically disordered proteins (IDPs). The aim is to embed measurements of conformational fluctuations of IDPs into a comprehensive and powerful mathematical model that allows for connecting the experimental data with a full picture of the underlying conformational dynamics.

PhD students:
Damir Sakhapov
Simon Schwarz